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Autor:
Qi Dai, Abdul Rezzak Hamzeh, Marquis P. Vawter, Nayna Sanathara, Lamees Alhassen, Lucas Pauluk, Jasmine Sakr, Amal Alachkar, Xuejie Wang, Ryan F. Yoshimura, Olivier Civelli, Anton Schulmann, Wedad Alhassen
Publikováno v:
International Journal of Neuropsychopharmacology
The international journal of neuropsychopharmacology, vol 23, iss 1
The international journal of neuropsychopharmacology, vol 23, iss 1
Background Evidence from anatomical, pharmacological, and genetic studies supports a role for the neuropeptide melanin concentrating hormone (MCH) system in modulating emotional and cognitive functions. Genome wide association (GWA) studies revealed
Autor:
Rui Jia, Fadao Tai, Xueni Zhang, Siyi Zhang, Yang Yang, Wenjuan Hou, Wei Yuan, Limin Wang, Zhenxiang Zhu, Zhixiong He
Publikováno v:
International Journal of Neuropsychopharmacology
Background Most previous studies have focused on the effects of social defeat in male juvenile individuals. Whether chronic social defeat stress in adulthood affects female emotion and the underlying mechanisms remains unclear. Methods Using highly a
Publikováno v:
International Journal of Neuropsychopharmacology
Background Prenatal stress is considered a risk factor for anxiety disorder. Downregulation in the expression of GABAergic gene, that is, glutamic acid decarboxylase 67, associated with DNA methyltransferase overexpression in GABAergic neurons has be
Autor:
Laura Lückemann, Matthew J Haight, Julia Kirchhof, Arne Herring, Ivo Bendix, Manfred Schedlowski, Kathy Keyvani, Meike Unteroberdörster, Martin Hadamitzky
Publikováno v:
International Journal of Neuropsychopharmacology
Background: Clinical data indicate that therapy with small-molecule immunosuppressive drugs is frequently accompanied by an incidence rate of neuropsychiatric symptoms. In the current approach, we investigated in rats whether repeated administration
Autor:
Anthony A. Grace, Millie Rincón-Cortés
Publikováno v:
International Journal of Neuropsychopharmacology
Background Stress constitutes a risk factor across several psychiatric disorders. Moreover, females are more susceptible to stress-related disorders, such as depression, than males. Although dopamine system underactivation is implicated in the pathop
Publikováno v:
International Journal of Neuropsychopharmacology
Background: The central nucleus of the amygdala (CeA) is a crucial component of the neuronal circuitry mediating aversive emotion. Its role in the negative affective states during drug withdrawal includes changes in opioidergic, GABAergic, and cortic
Publikováno v:
International Journal of Neuropsychopharmacology