Zobrazeno 81 - 90
of 179
pro vyhledávání: '"11"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5667, p 5667 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences
Volume 22
Issue 11
Kidney fibrosis is the final outcome of chronic kidney disease (CKD). Adenosine plays a significant role in protection against cellular damage by activating four subtypes of adenosine receptors (ARs), A1AR, A2AAR, A2BAR, and A3AR. A2AAR agonists prot
Autor:
Masako Miyahisa, Toru Maruyama, Tadashi Imafuku, Hiroshi Watanabe, Masafumi Fukagawa, Rui Fujimura, Shun Oshiro, Kai Tokumaru, Taisei Nagasaki, Hitoshi Maeda, Hiroto Nosaki, Yuto Hiramoto, Ryota Murata, Kento Nishida
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5600, p 5600 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences
Volume 22
Issue 11
An effective strategy is highly desirable for preventing acute kidney injury (AKI) to chronic kidney disease (CKD) transition. Thioredoxin-1 (Trx), a redox-active protein that has anti-oxidative and anti-inflammatory properties, would be a candidate
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5448, p 5448 (2021)
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5448, p 5448 (2021)
Volume 22
Issue 11
Matrix metalloproteinase 9 (MMP-9) expression is upregulated in vascular inflammation and participates in vascular remodeling, including aneurysm dilatation and arterial neointima development. Neointima at the arteriovenous (AV) fistula anastomosis s
Autor:
Tomoka Ikeda, Asami Nishikori, Rei Shibata, Midori Filiz Nishimura, Koh-Ichi Ohshima, Yuka Gion, Tadashi Yoshino, Yoshito Nishimura, Yasuharu Sato
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 4083, p 4083 (2021)
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 4083, p 4083 (2021)
Immunoglobulin G4-related disease (IgG4-RD) is a systemic disorder characterized by tissue fibrosis and intense lymphoplasmacytic infiltration, causing progressive organ dysfunction. Activation-induced cytidine deaminase (AID), a deaminase normally e
Autor:
Jiahua Zhang, Peishuang Yao, Wenli Han, Ying Luo, Yuke Li, Yang Yang, Hui Xia, Zhihao Chen, Qi Chen, Hong Wang, Lu Yang, Huan Li, Congli Hu, Haifeng Huang, Zhe Peng, Xiaodan Tan, Miaomiao Li, Junqing Yang
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6142
A growing body of research suggests that inflammatory insult contributes to the etiology of central nervous system diseases, such as depression, Alzheimer’s disease, and so forth. However, the effect of prenatal systemic inflammation exposure on of
Autor:
Jaqueline Stephanie Ley-Martínez, Jose Erick Ortega-Valencia, Oscar García-Barradas, Maribel Jiménez-Fernández, Esmeralda Uribe-Lam, Carlos Iván Vencedor-Meraz, Jacqueline Oliva-Ramírez
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6093
5-Lipoxygenase (5-LOX) converts arachidonic acid to lipidic inflammatory mediators such as leukotrienes (LTs). In diseases such as asthma, LTs contribute to a physiopathology that could be reverted by blocking 5-LOX. Natural products with anti-inflam
Autor:
Ryan M. Marquardt, Soo Hyun Ahn, Jake J. Reske, Ronald L. Chandler, Margaret G. Petroff, Tae Hoon Kim, Jae-Wook Jeong
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6067
A growing body of work suggests epigenetic dysregulation contributes to endometriosis pathophysiology and female infertility. The chromatin remodeling complex subunit AT-rich interaction domain 1A (ARID1A) must be properly expressed to maintain norma
Autor:
P. Garcia-Morales, Maria Fuentes-Baile, Miguel Saceda, Víctor Manuel Barberá, Camino de Juan Romero, Elizabeth Pérez-Valenciano, María Paz Ventero, Cristina Alenda, Jesús Sanz
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 22
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 21, Iss 8522, p 8522 (2020)
Volume 21
Issue 22
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 21, Iss 8522, p 8522 (2020)
23 p.-11 fig.
The combination of the choline binding domain of the amidase N-acetylmuramoyl-L-alanine (CLytA)-D-amino acid oxidase (DAAO) (CLytA-DAAO) and D-Alanine induces cell death in several pancreatic and colorectal carcinoma and glioblasto
The combination of the choline binding domain of the amidase N-acetylmuramoyl-L-alanine (CLytA)-D-amino acid oxidase (DAAO) (CLytA-DAAO) and D-Alanine induces cell death in several pancreatic and colorectal carcinoma and glioblasto
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8114, p 8114 (2020)
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8114, p 8114 (2020)
Chronic wounds are characterized by a localized pH change from acidic (healthy) to alkaline (unhealthy), which can be harnessed to act as a switch for drug release from a polymer medium covering the wound for improved healing. To realize this, a new
Autor:
Marina A. Zenkova, Evgeniya B. Logashenko, Kirill V Odarenko, Vadim A Talyshev, Valeriya O. Babich, Oksana V. Salomatina, Nariman F. Salakhutdinov, Andrey V. Markov, Aleksandra V Sen'kova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7876, p 7876 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences
Volume 21
Issue 21
Plant-extracted triterpenoids belong to a class of bioactive compounds with pleotropic functions, including antioxidant, anti-cancer, and anti-inflammatory effects. In this work, we investigated the anti-inflammatory and anti-oxidative activities of