Zobrazeno 1 - 10
of 127
pro vyhledávání: '"11"'
Autor:
Katarzyna Klak, B.M. Lidy Verburg-van Kemenade, Leszek Rydz, Magdalena Chadzinska, Magdalena Maciuszek
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 8954, p 8954 (2020)
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 8954, p 8954 (2020)
Macrophages are crucial not only for initiation of inflammation and pathogen eradication (classically polarized M1 macrophages), but also for inflammation inhibition and tissue regeneration (alternatively polarized M2 macrophages). Their polarization
Autor:
Paulina Koczurkiewicz-Adamczyk, Pawel E. Ferdek, Elżbieta Pękala, Reinoud Gosens, Agnieszka Jankowska, Grażyna Chłoń-Rzepa, Artur Świerczek, Elżbieta Wyska, Krzysztof Pociecha, Marietta Ślusarczyk, Katarzyna Wójcik-Pszczoła, Agnieszka A. Kusiak
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 11
International Journal of Molecular Sciences, 21(11):4008. MDPI AG
International Journal of Molecular Sciences, Vol 21, Iss 4008, p 4008 (2020)
Volume 21
Issue 11
International Journal of Molecular Sciences, 21(11):4008. MDPI AG
International Journal of Molecular Sciences, Vol 21, Iss 4008, p 4008 (2020)
Phosphodiesterase (PDE) inhibitors are currently a widespread and extensively studied group of anti-inflammatory and anti-fibrotic compounds which may find use in the treatment of numerous lung diseases, including asthma and chronic obstructive pulmo
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 11
Fischer, L, Lucendo Villarin, B, Hay, D & O'Farrelly, C 2020, ' Human PSC-derived hepatocytes express low levels of viral pathogen recognition receptors, but are capable of mounting an effective innate immune response ', International Journal of Molecular Sciences, vol. 21, no. 11, 3831 . https://doi.org/10.3390/ijms21113831
International Journal of Molecular Sciences, Vol 21, Iss 3831, p 3831 (2020)
Volume 21
Issue 11
Fischer, L, Lucendo Villarin, B, Hay, D & O'Farrelly, C 2020, ' Human PSC-derived hepatocytes express low levels of viral pathogen recognition receptors, but are capable of mounting an effective innate immune response ', International Journal of Molecular Sciences, vol. 21, no. 11, 3831 . https://doi.org/10.3390/ijms21113831
International Journal of Molecular Sciences, Vol 21, Iss 3831, p 3831 (2020)
Hepatocytes are key players in the innate immune response to liver pathogens but are challenging to study because of inaccessibility and a short half-life. Recent advances in in vitro differentiation of hepatocyte-like cells (HLCs) facilitated studie
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 11
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2734 (2019)
Volume 20
Issue 11
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2734 (2019)
Skullcapflavone II is a flavonoid derived from the root of Scutellaria baicalensis, a herbal medicine used for anti-inflammatory and anti-cancer therapies. We analyzed the effect of skullcapflavone II on the expression of matrix metalloproteinase-1 (
Autor:
Stefana Avram, Ciprian-Valentin Mihali, René Csuk, Ioana Zinuca Pavel, Danina Muntean, Flavia Baderca, Elena-Alina Moacă, Corina Danciu, Iulia Pinzaru, Andreea Cioca, Cristina Dehelean
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2828 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 11
International Journal of Molecular Sciences
Volume 20
Issue 11
Maslinic acid is a pentacyclic triterpene with a plethora of biological activities, including anti-inflammatory, antioxidant, antimicrobial, cardioprotective, and antitumor effects. New derivatives with improved properties and broad-spectrum activity
Autor:
Hyoungsu Kim, Seung-Hoon Baek, Donghyun Kim, Iljin Shin, Sun-Young Chang, Chan-Hee Yu, Beomseon Suh, Ok-Nam Bae, Eun-Hye Kim, Young-Jun Shin
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2607 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 11
International Journal of Molecular Sciences
Volume 20
Issue 11
The skin is an important physiological barrier against external stimuli, such as ultraviolet radiation (UV), xenobiotics, and bacteria. Dermal inflammatory reactions are associated with various skin disorders, including chemical-induced irritation an
Autor:
Mário Roberto Maróstica Júnior, Laura A. de la Rosa, Bruno Trevenzoli Favero, Adriano Costa de Camargo, Andrés R. Schwember, Marina Vilar Geraldi, Maressa Caldeira Morzelle, Fereidoon Shahidi, Emilio Alvarez-Parrilla, Marcelo Franchin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2644 (2019)
de Camargo, A C, Favero, B T, Morzelle, M C, Franchin, M, Alvarez-Parrilla, E, de la Rosa, L A, Geraldi, M V, Maróstica Júnior, M R, Shahidi, F & Schwember, A R 2019, ' Is Chickpea a Potential Substitute for Soybean? Phenolic Bioactives and Potential Health Benefits ', International Journal of Molecular Sciences, vol. 20, no. 11, 2644, pp. 1-42 . https://doi.org/10.3390/ijms20112644
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2644 (2019)
de Camargo, A C, Favero, B T, Morzelle, M C, Franchin, M, Alvarez-Parrilla, E, de la Rosa, L A, Geraldi, M V, Maróstica Júnior, M R, Shahidi, F & Schwember, A R 2019, ' Is Chickpea a Potential Substitute for Soybean? Phenolic Bioactives and Potential Health Benefits ', International Journal of Molecular Sciences, vol. 20, no. 11, 2644, pp. 1-42 . https://doi.org/10.3390/ijms20112644
Legume seeds are rich sources of protein, fiber, and minerals. In addition, their phenolic compounds as secondary metabolites render health benefits beyond basic nutrition. Lowering apolipoprotein B secretion from HepG2 cells and decreasing the level
Autor:
Hae Deun Kim, Pil-Hoon Park, Jaesuk Yun, Jin Tae Hong, Hyungok Chun, Hee Pom Lee, Chul Ju Hwang, Sang-Bae Han, Dong Young Choi, Ji Yeon Choi
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2632 (2019)
Volume 20
Issue 11
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2632 (2019)
Volume 20
Issue 11
Neuroinflammation is implicated in dopaminergic neurodegeneration. We have previously demonstrated that (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP), a selective signal transducer and activator of transcription 3 (STAT3) inhibit
Autor:
Lin Zhang, Jianglin Xiong, Xiangen Li, Xiuying Wang, Huiling Zhu, Zhixiao Tu, Shaokui Chen, Shuhui Wang, Guolong Zhang, Yulan Liu
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3697 (2018)
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3697 (2018)
This study was conducted to investigate whether medium-chain triglycerides (MCTs) attenuated lipopolysaccharide (LPS)-induced liver injury by down-regulating necroptotic and inflammatory signaling pathways. A total of 24 pigs were randomly allotted t
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3476 (2018)
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3476 (2018)
Interleukin 18 (IL-18) is one of the pro-inflammatory cytokines expressed by macrophages, suggesting that it plays important physiological and immunological functions, among the others: stimulation of natural killers (NKs) and T cells to interferon g