Zobrazeno 1 - 10
of 689
pro vyhledávání: ''
Autor:
Ryota Chijimatsu, Takuya Ishimoto, Kenji Takami, Takayoshi Nakano, Kosuke Ebina, Atsushi Goshima, Takashi Kanamoto, Akira Miyama, Yuki Etani, Yasukazu Yonetani, Masayuki Hamada, Gensuke Okamura, Ken Nakata, Makoto Hirao, Hideki Yoshikawa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 300, p 300 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Synovial mesenchymal stem cell (SMSC) is the promising cell source of cartilage regeneration but has several issues to overcome such as limited cell proliferation and heterogeneity of cartilage regeneration ability. Previous reports demonstrated that
Autor:
Saeed Y. Al-ramadan, Fatma J. Al-Saeedi, A. M. Soliman, Gamal M. Bekhet, Maged E. Mohamed, Rebai Ben Ammar, Medhat Ahmed El-Naggar, Peramaiyan Rajendran
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 217, p 217 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
In this study, kaempferol (KFL) shows hepatoprotective activity against zearalenone (ZEA)-induced oxidative stress and its underlying mechanisms in in vitro and in vivo models were investigated. Oxidative stress plays a critical role in the pathophys
Autor:
Margitta Elvers, Friedrich Reusswig, Christina Kohlmorgen, Henrike Hoermann, Yi Sun, Irena Krueger, Nadine Maurus, Jens W. Fischer, Maria Grandoch
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12168, p 12168 (2021)
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12168, p 12168 (2021)
Background: Vascular injury induces the exposure of subendothelial extracellular matrix (ECM) important to serve as substrate for platelets to adhere to the injured vessel wall to avoid massive blood loss. Different ECM proteins are known to initiate
Autor:
Francesco Callea, Hilda Angélica Martínez-Becerril, Magdalena Guerra-Crespo, Jerónimo F Garrido-Figueroa, Adriana Hernández-López, Marcia Hiriart, Rubén Argüero-Sánchez, Luis D. Bernal-Conde, Rodrigo Ramos-Acevedo, Francisco J Padilla-Godínez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12467, p 12467 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Dysfunction of cellular homeostasis can lead to misfolding of proteins thus acquiring conformations prone to polymerization into pathological aggregates. This process is associated with several disorders, including neurodegenerative diseases, such as
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12623, p 12623 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12623
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12623
As a source of growth factors for expediting wound healing and tissue regeneration, plasma-rich plasma (PRP) has been extensively applied in diverse fields including orthopaedics, ophthalmology, oral and maxillofacial surgery, dentistry, and gynaecol
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12599, p 12599 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
DNA molecules can adopt a variety of alternative structures. Among these structures are G-quadruplex DNA structures (G4s), which support cellular function by affecting transcription, translation, and telomere maintenance. These structures can also in
Autor:
Claire Rhee, Qi Gao, Elijah Ejun Huang, Rocky S. Tuan, Michael S. Gold, Hang Lin, Zhenyu Yao, Masahiro Maruyama, Bruce A. Bunnell, Shiqi Xiang, Zhong Li, Stuart B. Goodman
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12837, p 12837 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12837
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12837
Fibroblasts in the synovial membrane secrete molecules essential to forming the extracellular matrix (ECM) and supporting joint homeostasis. While evidence suggests that fibroblasts contribute to the response to joint injury, the outcomes appear to b
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12039, p 12039 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences
Volume 22
Issue 21
Purpose: The objective of the current study was to evaluate the effects of the autotaxin (ATX)–lysophosphatidic acid (LPA) signaling axis on the human trabecular meshwork (HTM) in two-dimensional (2D) and three-dimensional (3D) cultures of HTM cell
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12595, p 12595 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Mitogen-activated protein kinase (MAPK) signaling pathways are highly conserved regulators of eukaryotic cell function. These enzymes regulate many biological processes, including the cell cycle, apoptosis, differentiation, protein biosynthesis, and
Autor:
Jing Ye, Mirta M. L. Sousa, Gunn A. Hildrestrand, Luisa Luna, Katja Scheffler, Karine Øian Bjørås, Magnar Bjørås
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12924, p 12924 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The human brain requires a high rate of oxygen consumption to perform intense metabolic activities, accounting for 20% of total body oxygen consumption. This high oxygen uptake results in the generation of free radicals, including reactive oxygen spe