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Autor:
Paul Saftig, Wikky Tigchelaar-Gutter, Vincent Everts, Teun J. de Vries, Jolanda M. A. Hogervorst, Ineke D. C. Jansen
Publikováno v:
Jansen, I D C, Tigchelaar-Gutter, W, Hogervorst, J M A, de Vries, T J, Saftig, P & Everts, V 2020, ' LAMP-2 is involved in surface expression of rankl of osteoblasts in vitro ', International Journal of Molecular Sciences, vol. 21, no. 17, 6110, pp. 1-17 . https://doi.org/10.3390/ijms21176110
International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6110, p 6110 (2020)
International Journal of Molecular Sciences, 21(17):6110, 1-17. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6110, p 6110 (2020)
International Journal of Molecular Sciences, 21(17):6110, 1-17. Multidisciplinary Digital Publishing Institute (MDPI)
Lysosome associated membrane proteins (LAMPs) are involved in several processes, among which is fusion of lysosomes with phagosomes. For the formation of multinucleated osteoclasts, the interaction between receptor activator of nuclear kappa &beta
Autor:
Mari Hämäläinen, Antti Pemmari, Lauri J. Moilanen, Lauri Tuure, Riina Nieminen, Teemu Moilanen, E. Nummenmaa, Eeva Moilanen, Katriina Vuolteenaho
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 87, p 87 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Transient receptor potential ankyrin 1 (TRPA1) is a membrane-bound ion channel found in neurons, where it mediates nociception and neurogenic inflammation. Recently, we have discovered that TRPA1 is also expressed in human osteoarthritic (OA) chondro
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 167, p 167 (2021)
The early signaling events involved in oxidant recognition and triggering of oxidant-specific defense mechanisms to counteract oxidative stress still remain largely elusive. Our discovery driven comparative proteomics analysis revealed unique early s
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 112, p 112 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 1; Pages: 112
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 1; Pages: 112
International Journal of Molecular Sciences
Using a data driven analysis of a high-content screen, we have uncovered new regulators of epithelial-to-mesenchymal transition (EMT) induced cell migration. Our results suggest that increased expression of miR614 can alter cell intrinsic gene expres
Autor:
Ryota Chijimatsu, Takuya Ishimoto, Kenji Takami, Takayoshi Nakano, Kosuke Ebina, Atsushi Goshima, Takashi Kanamoto, Akira Miyama, Yuki Etani, Yasukazu Yonetani, Masayuki Hamada, Gensuke Okamura, Ken Nakata, Makoto Hirao, Hideki Yoshikawa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 300, p 300 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Synovial mesenchymal stem cell (SMSC) is the promising cell source of cartilage regeneration but has several issues to overcome such as limited cell proliferation and heterogeneity of cartilage regeneration ability. Previous reports demonstrated that
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13017, p 13017 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13017
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13017
The olfactory organ is an important chemoreceptor in vertebrates. However, the sexual disparities in gene expression patterns in the olfactory organ in fish remain unstudied. Here, we conducted a transcriptome analysis of the olfactory epithelium (OE
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12197, p 12197 (2021)
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12197, p 12197 (2021)
Salicylic acid (SA) and jasmonic acid (JA) are essential plant immune hormones, which could induce plant resistance to multiple pathogens. However, whether common components are employed by both SA and JA to induce defense is largely unknown. In this
Autor:
Yeun-Kyu Jang, Seung-Heon Baek
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 12079, p 12079 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 12079, p 12079 (2021)
Activating molecule in Beclin-1-regulated autophagy (AMBRA1), a negative regulator of tumorigenesis, is a substrate receptor of the ubiquitin conjugation system. ALDH1B1, an aldehyde dehydrogenase, is a cancer stem cell (CSC) marker that is required
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11976, p 11976 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Lymphatic endothelial cells (LECs) line the lymphatic vasculature and play a central role in the immune response. LECs have abilities to regulate immune transport, to promote immune cell survival, and to cross present antigens to dendritic cells. Sin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11883, p 11883 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 21; Pages: 11883
International Journal of Molecular Sciences, Vol 22, Iss 11883, p 11883 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 21; Pages: 11883
The failure of amyloid beta (Aβ) clearance is a major cause of Alzheimer’s disease, and the brain lymphatic systems play a crucial role in clearing toxic proteins. Recently, brain lymphatic endothelial cells (BLECs), a non-lumenized lymphatic cell