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Autor:
Carlos Miguel Marto, Inês Amaro, José Saraiva, Eunice Carrilho, Gianrico Spagnuolo, Ana Coelho, Beatriz Rascão, Anabela Paula, Inês Marcelino, Manuel Marques Ferreira
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 353, p 353 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cavity disinfection becomes an important step before a dental restorative procedure. The disinfection can be obtained cleaning the dental cavity with antimicrobial agents before the use of adhesive systems. The aim of this study was to conduct a syst
Autor:
Florence Lefranc, Luca X Zampieri, Rodrigue Rossignol, Raphaël Frédérick, Debora Grasso, Thibaut Vazeille, Elodie Dumon, Loïc Hamelin, Martina Sboarina, Etienne Sonveaux, Andrea Cacace, Pierre Sonveaux, Léopold Thabault
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11938, p 11938 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11938, p 11938 (2021)
Glioblastoma represents the highest grade of brain tumors. Despite maximal resection surgery associated with radiotherapy and concomitant followed by adjuvant chemotherapy with temozolomide (TMZ), patients have a very poor prognosis due to the rapid
Publikováno v:
Int. J. Mol. Sci.
International Journal of Molecular Sciences, Vol 22, Iss 12041, p 12041 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12041, p 12041 (2021)
International Journal of Molecular Sciences
Heparin and its derivatives are saving thousands of human lives annually, by successfully preventing and treating thromboembolic events. Although the mode of action during anticoagulation is well studied, their influence on cell behavior is not fully
Autor:
Vânia Vilas-Boas, Mathieu Vinken, Alanah Pieters, Eva Gijbels, Céline Parmentier, Audrey Baze, Kaat Leroy
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11005, p 11005 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences
Volume 22
Issue 20
Drug-induced liver injury, including cholestasis, is an important clinical issue and economic burden for pharmaceutical industry and healthcare systems. However, human-relevant in vitro information on the ability of other types of chemicals to induce
Autor:
Saša Đurović, Tomislav Tosti, Sofija Glumac, Jelena Đorđević, Iva Lakic, Nebojša Jasnić, Siniša Đurašević, Slavica Borković-Mitić, Aleksandra Ružičić, Slađan Z. Pavlović, Ilijana Grigorov, Sanja Tanasković Stanković, Zoran Todorovic
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9698, p 9698 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9698, p 9698 (2021)
Sepsis is a life-threatening condition caused by the dysregulated and overwhelming response to infection, accompanied by an exaggerated pro-inflammatory state and lipid metabolism disturbance leading to sequential organ failure. Meldonium is an anti-
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8324, p 8324 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Glioblastoma (GBM) is a highly lethal cancer that is universally refractory to the standard multimodal therapies of surgical resection, radiation, and chemotherapy treatment. Temozolomide (TMZ) is currently the best chemotherapy agent for GBM, but th
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7736, p 7736 (2021)
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7736, p 7736 (2021)
While the infection rate after primary total joint replacements (TJR) sits at 1–2%, for trauma-related surgery, it can be as high as 3.6 to 21.2% based on the type of trauma
the risk of reinfection after revision surgery is even higher. Curren
the risk of reinfection after revision surgery is even higher. Curren
Autor:
Kacper Pełka, Kyle P. Quinn, Michał Kopka, Albert Stachura, Paweł Włodarski, Piotr Pietruski, Jarosław Wejman, Ryszard Galus, Alan E. Woessner, Adriana M. Paskal, Wiktor Paskal
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7549, p 7549 (2021)
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7549, p 7549 (2021)
The aim of the study was to evaluate if a pre-incisional N-acetylcysteine (NAC) treatment altered the process of wound healing in a rat model. The dorsal skin of 24 Sprague-Dawley rats was incised in six locations. Before the incisions were made, ski
Autor:
Corina Andrei, Dragos Paul Mihai, Octavian Tudorel Olaru, Oana Cristina Seremet, Anca Zanfirescu, Anca Ungurianu, Simona Negres, Cosmin I Ciotu, Cornel Chirita, Cristina Elena Zbarcea, George Mihai Nitulescu, Michael Fischer
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7183, p 7183 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7183, p 7183 (2021)
Multiple sclerosis (MS) is a demyelinating, autoimmune disease that affects a large number of young adults. Novel therapies for MS are needed considering the efficiency and safety limitations of current treatments. In our study, we investigated the e
Autor:
Giuliano Ramadori
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7126, p 7126 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 7126, p 7126 (2021)
Hypercoagulation is one of the major risk factors for ICU treatment, mechanical ventilation, and death in critically ill patients infected with SARS-CoV-2. At the same time, hypoalbuminemia is one risk factor in such patients, independent of age and