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of 46
pro vyhledávání: ''
Autor:
Lars H. Engelholm, Eric Santoni-Rugiu, Henrik Gårdsvoll, Oliver Krigslund, Rikke Raagaard Sørensen, Christoffer Nielsen, Pınar Çakılkaya, Henrik J. Jürgensen, Niels Behrendt
Publikováno v:
Çakılkaya, P, Sørensen, R R, Jürgensen, H J, Krigslund, O, Gårdsvoll, H, Nielsen, C F, Santoni-Rugiu, E, Behrendt, N & Engelholm, L H 2021, ' The Collagen Receptor uPARAP in Malignant Mesothelioma : A Potential Diagnostic Marker and Therapeutic Target ', International Journal of Molecular Sciences, vol. 22, no. 21, 11452 . https://doi.org/10.3390/ijms222111452
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11452, p 11452 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11452, p 11452 (2021)
Malignant mesothelioma (MM) is a highly aggressive cancer with limited therapeutic options. We have previously shown that the endocytic collagen receptor, uPARAP, is upregulated in certain cancers and can be therapeutically targeted. Public RNA expre
Autor:
Hideki Kobara, Kayo Hirose, Shintaro Fujihara, Hisakazu Iwama, Tsutomu Masaki, Noriko Nishiyama
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4789, p 4789 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences
Volume 22
Issue 9
Esophageal squamous cell carcinoma (ESCC) has a poor prognosis when diagnosed at an advanced stage, and early detection and treatment are essential to improve survival. However, intraobserver and interobserver variation make the diagnosis of superfic
Autor:
Rina Meidan, Nina Schmid, Artur Mayerhofer, Kim-Gwendolyn Dietrich, Doris Mayr, Ignasi Forné, Magdalena Szymanska, Alexander Burges
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2047, p 2047 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Sirtuins (SIRTs) are NAD+-dependent deacetylases that regulate proliferation and cell death. In the human ovary, granulosa cells express sirtuin 1 (SIRT1), which has also been detected in human tumors derived from granulosa cells, i.e., granulosa cel
Autor:
Udo Jeschke, Bastian Czogalla, Christina Kuhn, Martina Rahmeh, S Meister, Doris Mayr, Anna Hester, Tom Degenhardt, Sven Mahner, Anna Trebo, Nina Ditsch, Thomas Kolben, Elisa Schmoeckel
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2000, p 2000 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are involved in various immune cell-mediated diseases. Their role in cancer is poorly investigated, and research focusses on Siglec-expression on immune cells interacting with tumor cells. Thi
Autor:
Ki Cheong Park, Hyeok Jun Yun, Hee Jun Kim, Hang Seok Chang, Ho Jin Chang, Jung Min Kim, Cheong Soo Park, Sang Yong Kim
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 536, p 536 (2021)
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 536, p 536 (2021)
Volume 22
Issue 2
Anaplastic thyroid cancer (ATC) is an undifferentiated and advanced form of thyroid cancer, accompanied with a high ratio of epigenetic adjustment, which occurs more than genetic mutations. In this study, we aimed to evaluate the synergistic anticanc
Autor:
Gareth I. Owen, Tomas de Mayo, Enrique Norero, Franz Villarroel-Espindola, Maria Alejandra Alarcon, Alejandro H. Corvalan, Wilda Olivares, Julio D. Amigo, Gonzalo Carrasco-Avino, Marcelo Garrido, Miguel Cordova-Delgado, Natalia Landeros, Matías Muñoz-Medel, Ignacio A. Wichmann, Arnoldo Riquelme
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9472, p 9472 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences
Volume 21
Issue 24
Reprimo-like (RPRML) is an uncharacterized member of the Reprimo gene family. Here, we evaluated the role of RPRML and whether its regulation by DNA methylation is a potential non-invasive biomarker of gastric cancer. RPRML expression was evaluated b
Autor:
Elmir Graf, Gregor Hörmann, Peter Valent, Reinhard Stauder, Temeida Graf, Thomas Nösslinger, Agnes Barna, Sigrid Machherndl-Spandl, Leopold Öhler, Michael Gurbisz, Eva Jäger, Armin Zebisch, Michael Pfeilstöcker, Heinz Sill, Rajko Kusec, Klaus Geissler
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6057, p 6057 (2020)
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6057, p 6057 (2020)
We have originally reported that colony-forming units granulocyte/macrophage (CFU-GM) formation is an in vitro feature of chronic myelomonocytic leukemia (CMML) and a strong predictor for short survival. Elucidation of the molecular basis underlying
Autor:
Iwona Bednarz-Misa, Małgorzata Krzystek-Korpacka, Paulina Fortuna, Dorota Diakowska, Natalia Jamrozik
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4509, p 4509 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 12
International Journal of Molecular Sciences
Volume 21
Issue 12
Gastric (GC) and esophageal (EC) cancers are highly lethal. Better understanding of molecular abnormalities is needed for new therapeutic targets and biomarkers to be found. Expression of 18 cancer-related genes in 31 paired normal-tumor samples was
Autor:
Asako Doi, Hiroyuki Ariyasu, Hidefumi Inaba, Shinsuke Uraki, Hiroto Furuta, Takashi Akamizu, Shozo Yamada, Naoko Inoshita, Noriaki Fukuhara, Shuhei Morita, Ken Takeshima, Hiroshi Nishioka, Naoyuki Nakao
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2831, p 2831 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 8
International Journal of Molecular Sciences
Volume 21
Issue 8
Mismatch repair genes mutS homologs 6/2 (MSH6/2) expressions are involved in tumor growth and programmed cell death 1 ligand 1 (PD-L1) expression in tumor immunity, but the direct association with pituitary adenomas (PAs) is not well understood. We a
Autor:
Galina M. Kazanskaya, Anastasia V. Suhovskih, Alexandra Y. Tsidulko, Elvira V. Grigorieva, Svetlana V. Aidagulova, Alexander M. Volkov
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 4
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1301 (2020)
Volume 21
Issue 4
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1301 (2020)
Adjuvant chemoradiotherapy is a standard treatment option for glioblastoma multiforme (GBM). Despite intensive care, recurrent tumors developed during the first year are fatal for the patients. Possibly contributing to this effect, among other causes