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Autor:
Christina Weisheit, Mark Coburn, Stilla Frede, Christian Putensen, Valentina Zschernack, Stefan Muenster, Birte Dierig, Georg Baumgarten
Publikováno v:
International Journal of Immunopathology and Pharmacology
Sepsis is a leading cause of death worldwide, despite the use of multimodal therapies. Common antibiotic regimens are being affected by a rising number of multidrug-resistant pathogens, and new therapeutic approaches are therefore needed. Antibiotics
Publikováno v:
International Journal of Immunopathology and Pharmacology
Autoimmune lymphoproliferative syndrome (ALPS) usually presents in childhood with fever, nonmalignant splenomegaly, and lymphadenopathy along with cytopenia, which is caused by mutations in the FAS apoptotic pathway. The TCRαβ + CD4/CD8 double-nega
Publikováno v:
International Journal of Immunopathology and Pharmacology
Septic shock (SS) leads to a high mortality rate for sepsis patients. Norepinephrine (NE) is a preferred vasoactive agent in SS treatment. This study aimed to assess the effects of NE at different administration time and NE combined with SP treatment
Publikováno v:
International Journal of Immunopathology and Pharmacology
NLRP3 inflammasome activation results in severe liver inflammation and injury. Saikosaponin-d (SSd) possesses anti-inflammatory and hepatoprotective effects. This study aimed to determine the protective effects of SSd on carbon tetrachloride (CCl4)-i
Autor:
Cristiana Stellato, Ilaria De Pascale, Francesco Antonio Salzano, Nicola Rosa, Maddalena De Bernardo
Publikováno v:
International Journal of Immunopathology and Pharmacology
This case report describes an unusual case of late-onset larynx angioedema after ranibizumab intravitreal injection. A 72-year-old female patient presented to our clinic for decreased vision; right eye (RE) fundoscopy and optical coherence tomography
Autor:
Tanja D. de Gruijl, Hans J. van der Vliet, Charlotte M. Huijts, Saskia J. A. M. Santegoets, Tamarah D. de Jong, Henk M.W. Verheul
Publikováno v:
International Journal of Immunopathology and Pharmacology, 30(4), 341-352. SAGE Publications Inc.
International Journal of Immunopathology and Pharmacology
Huijts, C M, Santegoets, S J, de Jong, T D, Verheul, H M, de Gruijl, T D & van der Vliet, H J 2017, ' Immunological effects of everolimus in patients with metastatic renal cell cancer ', International Journal of Immunopathology and Pharmacology, vol. 30, no. 4, pp. 341-352 . https://doi.org/10.1177/0394632017734459
International Journal of Immunopathology and Pharmacology
Huijts, C M, Santegoets, S J, de Jong, T D, Verheul, H M, de Gruijl, T D & van der Vliet, H J 2017, ' Immunological effects of everolimus in patients with metastatic renal cell cancer ', International Journal of Immunopathology and Pharmacology, vol. 30, no. 4, pp. 341-352 . https://doi.org/10.1177/0394632017734459
The mammalian target of rapamycin (mTOR) is a crucial kinase present in all cells. Besides its role in the regulation of cell-growth, proliferation, angiogenesis, and survival of malignant tumors, mTOR additionally plays an important role in immune r
Autor:
Jing-Can Wu, Guiyi Ji, Miaomiao Zhang, Guo Chen, Mei Feng, Jian-Qing He, Qianqian Liu, Shouquan Wu, Yu Wang
Publikováno v:
International Journal of Immunopathology and Pharmacology
Anti-tuberculosis drug-induced liver injury (ATLI) is common during the treatment of tuberculosis (TB). As an important enzyme in the metabolism of many drugs, UGT2B7 (uridine diphosphate glucuronyl transferase 2B7) was associated with drug-induced l
Autor:
Oriana Trubiani, Thangavelu Soundara Rajan, Francesca Diomede, Placido Bramanti, Emanuela Mazzon, Sabrina Giacoppo
Publikováno v:
International Journal of Immunopathology and Pharmacology
Research in recent years has largely explored the immunomodulatory effects of mesenchymal stem cells (MSCs) and their secretory products, called “secretome,” in the treatment of neuroinflammatory diseases. Here, we examined whether such immunosup
Autor:
Michael Rukavishnikov, Ekaterina Mogilnaya, Elena Mikhailova, Sergey Arkhipov, A I Autenshlyus, Nikolay Varaksin, Valentina Arkhipova, Igor Marinkin
Publikováno v:
International Journal of Immunopathology and Pharmacology
In recent years, the concept of formation of a sufficiently autonomous cytokine network in a malignant tumour has emerged. In this regard, the data on the role of this network and its signalling pathways in the process of metastasis are an interestin
Publikováno v:
International Journal of Immunopathology and Pharmacology
Chronic inflammation is thought to be a major driving force for the development of colitis-associated colorectal cancer (CAC). As one member of proinflammatory cytokine family, granulocyte macrophage colony-stimulating factor (GM-CSF) has been identi