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Publikováno v:
International Journal of Immunopathology and Pharmacology
Autoimmune lymphoproliferative syndrome (ALPS) usually presents in childhood with fever, nonmalignant splenomegaly, and lymphadenopathy along with cytopenia, which is caused by mutations in the FAS apoptotic pathway. The TCRαβ + CD4/CD8 double-nega
Publikováno v:
International Journal of Immunopathology and Pharmacology
Septic shock (SS) leads to a high mortality rate for sepsis patients. Norepinephrine (NE) is a preferred vasoactive agent in SS treatment. This study aimed to assess the effects of NE at different administration time and NE combined with SP treatment
Autor:
Tanja D. de Gruijl, Hans J. van der Vliet, Charlotte M. Huijts, Saskia J. A. M. Santegoets, Tamarah D. de Jong, Henk M.W. Verheul
Publikováno v:
International Journal of Immunopathology and Pharmacology, 30(4), 341-352. SAGE Publications Inc.
International Journal of Immunopathology and Pharmacology
Huijts, C M, Santegoets, S J, de Jong, T D, Verheul, H M, de Gruijl, T D & van der Vliet, H J 2017, ' Immunological effects of everolimus in patients with metastatic renal cell cancer ', International Journal of Immunopathology and Pharmacology, vol. 30, no. 4, pp. 341-352 . https://doi.org/10.1177/0394632017734459
International Journal of Immunopathology and Pharmacology
Huijts, C M, Santegoets, S J, de Jong, T D, Verheul, H M, de Gruijl, T D & van der Vliet, H J 2017, ' Immunological effects of everolimus in patients with metastatic renal cell cancer ', International Journal of Immunopathology and Pharmacology, vol. 30, no. 4, pp. 341-352 . https://doi.org/10.1177/0394632017734459
The mammalian target of rapamycin (mTOR) is a crucial kinase present in all cells. Besides its role in the regulation of cell-growth, proliferation, angiogenesis, and survival of malignant tumors, mTOR additionally plays an important role in immune r
Autor:
Jing-Can Wu, Guiyi Ji, Miaomiao Zhang, Guo Chen, Mei Feng, Jian-Qing He, Qianqian Liu, Shouquan Wu, Yu Wang
Publikováno v:
International Journal of Immunopathology and Pharmacology
Anti-tuberculosis drug-induced liver injury (ATLI) is common during the treatment of tuberculosis (TB). As an important enzyme in the metabolism of many drugs, UGT2B7 (uridine diphosphate glucuronyl transferase 2B7) was associated with drug-induced l
Autor:
Oriana Trubiani, Thangavelu Soundara Rajan, Francesca Diomede, Placido Bramanti, Emanuela Mazzon, Sabrina Giacoppo
Publikováno v:
International Journal of Immunopathology and Pharmacology
Research in recent years has largely explored the immunomodulatory effects of mesenchymal stem cells (MSCs) and their secretory products, called “secretome,” in the treatment of neuroinflammatory diseases. Here, we examined whether such immunosup
Autor:
Michael Rukavishnikov, Ekaterina Mogilnaya, Elena Mikhailova, Sergey Arkhipov, A I Autenshlyus, Nikolay Varaksin, Valentina Arkhipova, Igor Marinkin
Publikováno v:
International Journal of Immunopathology and Pharmacology
In recent years, the concept of formation of a sufficiently autonomous cytokine network in a malignant tumour has emerged. In this regard, the data on the role of this network and its signalling pathways in the process of metastasis are an interestin
Autor:
José Luís González-Cespón, Carmen Rodríguez Cerdeira, Beatriz Sánchez-Blanco, Elena Sanchez-Blanco
Publikováno v:
International Journal of Immunopathology and Pharmacology
Psychiatric evaluation presents a significant challenge because it conceptually integrates the input from multiple psychopathological approaches. Recent technological advances in the study of protein structure, function, and interactions have provide
Autor:
Abdel-Rahman N. Zekri, Mamdooh Ghoneum, Tarneem Darwish, Hosny Salama, Magda Shaheen, Eman Medhat
Publikováno v:
International Journal of Immunopathology and Pharmacology. 29:647-653
Current treatments for Hepatitis C virus (HCV) have severe side effects and are very expensive. There is a need to explore effective natural therapies against HCV that are less toxic and more cost-effective. In the current study, 37 chronic HCV patie
Publikováno v:
International Journal of Immunopathology and Pharmacology
Alemtuzumab, an anti-CD52 monoclonal antibody, is effective in the treatment of relapsing–remitting multiple sclerosis (RRMS). Common adverse effects include the development of autoimmune diseases, and Graves’ disease is one of the most frequent
Publikováno v:
International Journal of Immunopathology and Pharmacology
Innate immunity plays a central role in neoplasms, including those affecting the central nervous system (CNS). Nowadays, tumors classification, especially that regarding gliomas, is based on molecular features such as mutations in isocitrate dehydrog