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Autor:
Binyou Liao, Xingchen Ye, Xi Chen, Min Liao, Chengguang Zhu, Lei Cheng, Xuedong Zhou, Yujie Zhou, Biao Ren
Publikováno v:
International journal of antimicrobial agents. 58(3)
Oral candidiasis, especially caused by Candida albicans, is the most common fungal infection of the oral cavity. The increase in drug resistance and lack of new antifungal agents call for new strategies of antifungal treatment. This study repurposed
Publikováno v:
International journal of antimicrobial agents. 58(5)
Acanthamoebae are opportunistic pathogens that cause serious infections, including Acanthamoeba keratitis, a sight-threatening disease affecting mainly contact lens wearers, and granulomatous amoebic encephalitis, an infection of the central nervous
Autor:
Torahiko Okubo, Hiroyuki Yamaguchi, Yutaka Tamura, Masaru Usui, Jeewan Thapa, Takaki Hasegawa, Akira Fukuda
Publikováno v:
International Journal of Antimicrobial Agents. 54:831-833
Autor:
Margarita Kyriakidou, Matthew E. Falagas, Anthony R.M. Coates, Georgios L Voulgaris, Panagiota Giakkoupi, Yanmin Hu, Alkiviadis Vatopoulos, Kyriaki Tryfinopoulou
Publikováno v:
International Journal of Antimicrobial Agents. 53:855-858
BACKGROUND: New antibiotics are urgently needed for the treatment of multidrug resistant infections. However, the production of novel antibiotics is diminishing. The enhancement of activity of available antibiotics through synergistic combination dru
Publikováno v:
International Journal of Antimicrobial Agents. 52:608-615
This study evaluated the in vitro activity of oritavancin in combination with rifampin or gentamicin against methicillin-resistant Staphylococcus epidermidis (MRSE) biofilms. Oritavancin, rifampin, and gentamicin were tested against 20 MRSE isolates
Autor:
Joseph Papaparaskevas, Michael Samarkos, George L. Daikos, Angeliki Pantazatou, Antonios Markogiannakis, Mina Balaska, Giannoula S. Tansarli, Marina Mantzourani, Katerina Polonyfi
Publikováno v:
International Journal of Antimicrobial Agents. 52:397-403
Colistin is often the only available treatment option against infections caused by carbapenemase-producing Klebsiella pneumoniae (CP-Kp). In this study, the evolution of colistin resistance among CP-Kp and its relationship with colistin use in a tert
Autor:
Huajun Zheng, Yuancheng Chen, Xingchen Bian, Phillip J. Bergen, Jian Li, Xiaofen Liu, Meiqing Feng, Sichao Song, Jing Zhang
Publikováno v:
International journal of antimicrobial agents. 57(2)
Aims: Polymyxin-based combination therapy is often used to treat carbapenem-resistant Acinetobacter baumannii (A. baumannii) infections. Although sulbactam is intrinsically active against A. baumannii, few studies have investigated colistin/sulbactam
Autor:
Anthony R.M. Coates, Yanmin Hu
Publikováno v:
International journal of antimicrobial agents. 57(4)
Infections caused by carbapenem-resistant Enterobacterales are difficult to treat. Colistin is the last-resort drug for the treatment of these infections, however colistin resistance has emerged in animals and humans. This study investigated the in v
Publikováno v:
International journal of antimicrobial agents. 56(2)
The number of invasive fungal infections has increased dramatically over recent years, leading to high morbidity and mortality of immunocompromised patients. Candida albicans is the most common cause of life-threatening disseminated candidiasis among
Autor:
Predrag Novak, Ivan Grgičević, Iva Habinovec, Ivana Mikulandra, Vedrana Radovanović, Mirjana Bukvić, Mihailo Banjanac, Branimir Bertoša
Publikováno v:
International journal of antimicrobial agents. 56(5)
Increasing bacterial resistance to existing antibiotics presents a serious threat to human health, and new antibacterial agents are desperately needed. Unfortunately, the number of newly marketed antibiotics has decreased dramatically in recent years