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Publikováno v:
Int Arch Allergy Immunol
Introduction: Few studies assess biologicals such as, omalizumab, mepolizumab, benralizumab, and dupilumab in patients suffering from chronic rhinosinusitis with nasal polyposis (CRSwNP). The reported success rate in these studies differ, and it rema
Publikováno v:
Int Arch Allergy Immunol
Introduction: The stratum corneum contains several growth factors and cytokines that are synthesized in keratinocytes. We previously reported that the amount of interleukin-8 in the stratum corneum (scIL-8) is related to the severity of local skin in
Publikováno v:
International Archives of Allergy and Immunology. 182:83-93
Background:Chronic idiopathic urticaria (CIU) represents a common skin disorder often characterized by mast cell activation and secretion of histamine and other proinflammatory factors. E-selectin (SELE) has been implicated in the pathogenesis of com
Publikováno v:
International Archives of Allergy and Immunology. 182:32-38
Background: Soy isoflavones and their metabolites such as equol have been associated with a reduced risk of hormone-sensitive tumors and metabolic syndromes. However, individual soy isoflavones and equol levels in atopic dermatitis remain uninvestiga
Autor:
Rosa Metella Refini, Elena Bargagli, Francesco Bianchi, Paolo Cameli, Laura Bergantini, Miriana d'Alessandro, Piersante Sestini
Publikováno v:
International Archives of Allergy and Immunology. 181:746-753
Background: New anti-IL-5 antibodies, mepolizumab and benralizumab, have recently been approved for severe asthma, sharing the same inclusion criteria. Objective: To contribute on biomarkers research leading to the personalized choice, we investigate
Autor:
Ekaterini Tiligada, Andriana Kavallari, Maria Kakolyri, Caterina Chliva, Flora Strikou, Michael Makris
Publikováno v:
International Archives of Allergy and Immunology. 181:24-30
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) represent one of the most prevalent causes of drug hypersensitivity reactions (DHRs), yet the underlying processes are far from clear. Despite the established role of histamine in allergic re
Publikováno v:
International Archives of Allergy and Immunology. 179:297-303
Background: Mucociliary clearance is one of the most important protective functions of the airway. Previous studies, checking the influence of allergic rhinitis (AR) on mucociliary clearance time (MCT), were made on small patient groups and brought c
Publikováno v:
International Archives of Allergy and Immunology. 178:248-254
Background: Most children diagnosed with β-lactam allergy based only on history are not truly allergic, and mislabeling leads to use of less effective and more costly alternative broader-spectrum antibiotics, significantly increasing drug resistance
Publikováno v:
International Archives of Allergy and Immunology. 175:237-245
Background: A history of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity with cross-intolerance to several drugs is common in some patients with coronary artery disease. We present a series of patients with acute coronary syndrome underg
Autor:
Maria Sole Chimenti, Gianluca Draghessi, Claudia Canofari, Claudia Valeri, Paola Conigliaro, Roberto Perricone, Carlo Nucci, Gianluca Aloe, Paola Triggianese, Massimo Cesareo
Publikováno v:
International Archives of Allergy and Immunology. 177:45-56
Background: Retinal involvement in systemic lupus erythematosus (SLE) and Sjögren syndrome (SS) may be subclinical and thus underdiagnosed. Objectives: We aimed at evaluating morphological and functional visual abnormalities in a cohort of SLE and S