Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kyung-Sang Yu"'
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 58:354-362
Objective Asthma patients often have co-existing symptoms of allergic rhinitis and are often prescribed with both asthma and rhinitis treatments such as montelukast and levocetirizine. The objective of this study was to compare the pharmacokinetic pr
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 55:194-200
BACKGROUNDS Baclofen is used as a skeletal muscle relaxant for multiple sclerosis patients. It depresses the transmission of monosynaptic and polysynaptic reflex by stimulating GABAβ (gamma-aminobutyric acid) receptors. OBJECTIVES The aim of this st
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 54:928-934
Objective This study had a single-dose, randomized, open-label, 2-period, and 2-sequence crossover design to evaluate pharmacokinetic (PK) bioequivalence between the test and reference formulations. Methods and materials Of the 34 healthy male volunt
Autor:
Dongseong Shin, Seung Hwan Lee, Sang-Goo Shin, Joo Youn Cho, KyoungSoo Lim, Kyung Sang Yu, In-Jin Jang, Kwang-Hee Shin
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 50:722-728
OBJECTIVE Fesoterodine is a pro-drug of the active metabolite 5-hydroxymethyl tolterodine (5-HMT), a muscarinic receptor antagonist. This study aimed to evaluate the safety profile and pharmacokinetic characteristics of multiple oral doses of sustain
Autor:
Kyu Pyo Kim, Seo Hyun Yoon, Kyoung Soo Lim, In-Jin Jang, Bo Yeun Yang, Jae Sung Lee, Jae Min Jung, Yun Sang Lee, Kyung Sang Yu, Ji Who Kim, Kwang-Hee Shin
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 50:224-232
OBJECTIVE This study explored microdosing methods for evaluating the distribution and pharmacokinetics (PK) of a central nervous system (CNS) drug candidate. METHODS We used sertraline as a model drug. In this open-label, one-arm, three-period, multi
Autor:
Sumin Yoon, In-Jin Jang, Kyung Sang Yu, Sukyoun Shin, Joo Youn Cho, Kwan Kim, Myoung Kyu Park, Tae Eun Kim, Kyusoon Shin
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 49:672-678
BACKGROUND Sertraline is a naphthalenamine derivative which has the effect of selective serotonin reuptake inhibition. It has been used for major depression, and obsessive compulsive disorder. This study was performed to evaluate the pharmacokinetic
Autor:
In-Jin Jang, Hwang Gyun Jeon, Tae Eun Kim, Sumin Yoon, Kyung Sang Yu, Seung Hwan Lee, Sukyoun Shin
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 49:688-695
Background Probucol is indicated for primary hyperlipidemia and for hypercholesterolemia with hypertriglyceridemia. The objective of this study was to evaluate the tolerability and pharmacokinetics of probucol by multiple oral administration in healt