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Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 57:610-619
This study investigates the protective effect of small peptides from Periplaneta americana (SPPA) on hydrogen peroxide (H2O2)–induced apoptosis of ovarian granular cells. H2O2 was applied to human ovarian granular cells (KGN cell strains). Cell via
Autor:
Yuko Hara-Saito, Kenji Izumi, Hiroko Kato, Naoaki Saito, Atsushi Uenoyama, Ritsuo Takagi, Aki Shiomi
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 56:452-479
The differences between oral mucosa and skin wound healing involving hypoxic responses of fibroblasts are poorly elucidated. In this study, we aimed to study the different hypoxic responses between oral and skin fibroblasts embedded in a three-dimens
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 56:129-144
During hematogenous metastasis, cancer cells escape from primary lesions and enter into the circulatory system, and only a few can colonize distant organs. However, the mechanism of cell survival and metastasis in the hematopoietic environment remain
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 56:145-153
Cervical cancer is among the most prevalent malignancies for women. An increasing number of evidences have been proved that long non-coding RNAs (lncRNAs) play significant role in the initiation and progression of cervical cancer. However, the functi
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 55:331-340
Tetrandrine is a bisbenzylisoquinoline alkaloid known to exhibit anticancer activity against different cancers. In the present study, the cytotoxic effect of tetrandrine isolated from Cyclea peltata on pancreatic (PANC-1) and breast (MDA-MB-231) canc
Autor:
Lei Lei, Haixiang Sun, Lijun Ding, Xiaoqiang Sheng, Jingyu Liu, Shanshan Wang, Lu Xu, Guijun Yan, Mengyuan Liu, Xin Zhen, Yanjun Yang
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 55:302-311
Premature ovarian failure (POF) is a refractory disease; one of the most important goals of treatment is to improve fertility. In the study, collagen scaffold loaded with human umbilical cord-derived mesenchymal stem cells (collagen/UC-MSCs) transpla
Autor:
Tadashi Kondo, Shunichi Toki, Marimu Sakumoto, Kumiko Shiozawa, Fusako Kito, Rieko Oyama, Akira Kawai, Zhiwei Qiao, Akihiko Yoshida
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 55:62-73
Dermatofibrosarcoma protuberans (DFSP) is a common type of dermal sarcoma, characterized by the presence of the unique collagen type I alpha 1 chain (COL1A1)-PDGFB translocation, which causes constitutive activation of the platelet-derived growth fac
Autor:
Fusako Kito, Mami Takahashi, Zhiwei Qiao, Akira Kawai, Tadashi Kondo, Shunichi Toki, Marimu Sakumoto, Akihiko Yoshida, Rei Noguchi, Yoshikazu Tanzawa, Rieko Oyama
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 54:770-778
Ewing's sarcoma is an aggressive mesenchymal tumor characterized by the presence of a unique EWSR1-FLI1 translocation. Ewing's sarcoma primarily occurs in the bone and soft tissues. Cell lines enable researchers to investigate the molecular backgroun
Autor:
Mahdi Paryan, Maryam Sharif Beigli, Vahid Kia, Samira Mohammadi-Yeganeh, Vahedeh Hosseini, Ameneh Koochaki
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 54:621-628
Breast cancer is the first common cancer among women worldwide. One of the major signaling pathways playing a role in the onset and progression of this disease is PI3K/Akt/mTOR, which can be inhibited by PTEN. miRNAs are small non-coding molecules th
Autor:
Sawsan Shraim, Mariam Hasan, May Al-Majawleh, Lama Hamadneh, Yazun Jarrar, Bashaer Abu-Irmaileh
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 54:331-334
The levels of DNA methylation and their role in gene expression are key factors that could affect diagnosis, prognosis, and treatment options of different diseases. In this study, the methylation levels of 22 genes that are mostly correlated to breas