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Autor:
Ulf Dittmer, Pedro Milanez-Almeida, Tim Sparwasser, Deepika Watts, Christian T. Mayer, Nanna Fyhrquist, Jochen Huehn, Katharina Lahl, Manfred Kopf, Karsten Kretschmer, Barry T. Rouse
Publikováno v:
Immunity, Inflammation and Disease. 2:162-165
Several mechanisms enable immunological self-tolerance. Regulatory T cells (Tregs) are a specialized T cell subset that prevents autoimmunity and excessive immune responses, but can also mediate detrimental tolerance to tumors and pathogens in a Foxp