Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ye Zheng"'
Autor:
Jovylyn Gatchalian, Chin-San Loo, Bhargav Venkatraghavan, Yuqiong Liang, Josephine Ho, Ye Zheng, Diana C. Hargreaves, Mingjun Xie, Mathias Leblanc
Publikováno v:
Immunity
Summary Regulatory T (Treg) cells play a pivotal role in suppressing auto-reactive T cells and maintaining immune homeostasis. Treg cell development and function are dependent on the transcription factor Foxp3. Here, we performed a genome-wide CRISPR
Autor:
Ye Zheng
Publikováno v:
Immunity. 47:211-214
Hayatsu et al. (2017) reveal that a FOXP3 mutant found in some patients afflicted with the autoimmune disease IPEX has broadened DNA-recognition specificity, directly repressing the expression of the gene encoding the transcription factor Batf. Their
Autor:
Tissa Hata, Xu Chen, Christian F. Guerrero-Juarez, Marc C. Liggins, Stella X. Chen, Yuqiong Liang, Ye Zheng, Min Li, Ling-juan Zhang, Richard L. Gallo, Maksim V. Plikus, Yun Tong, Fengwu Li, Hao Chen
Publikováno v:
Immunity. 50:121-136.e5
Dermal fibroblasts (dFBs) resist infection by locally differentiating into adipocytes and producing cathelicidin antimicrobial peptide in response to Staphylococcus aureus (S. aureus). Here, we show that neonatal skin was enriched with adipogenic dFB
Publikováno v:
Immunity. 16:257-270
Despite the established role of dendritic cells (DCs) in regulating T lymphocyte activation, intracellular mechanisms responsible for controlling DC function are largely undefined. Here, we have studied DCs from mice deficient in the p50, RelA, and c