Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Steven C. Hunt"'
Autor:
Maciej Tomaszewski, Fadi J. Charchar, Peter S. Braund, Steven C. Hunt, Katrina J Scurrah, Cara J Busst, Lisa D.S. Bloomer, Paul N. Hopkins, Justine A. Ellis, Stephen B. Harrap, Timothy A. Barnes, N J Samani
Publikováno v:
Hypertension. 58:1073-1078
Variants in the gene encoding the γ-subunit of the epithelial sodium channel ( SCNN1G) are associated with both Mendelian and quantitative effects on blood pressure. Here, in 4 cohorts of 1611 white European families composed of a total of 8199 indi
Autor:
Larry D. Atwood, David M. Kent, Paul N. Hopkins, Nicola J. Camp, Steven C. Hunt, Georgios D Kitsios, Elias Zintzaras
Publikováno v:
Hypertension. 50:557-564
Genome scans for identifying susceptibility loci for pulse pressure have produced inconclusive results. A heterogeneity-based genome search meta-analysis was applied to available genome-scan data on pulse pressure. A genome search meta-analysis divid
Autor:
Sandra J. Hasstedt, Hilary Coon, Paul N. Hopkins, Yuanpei Xin, Steven C. Hunt, Lily Wu, Richard M. Cawthon
Publikováno v:
Hypertension. 47:532-536
The NaHCO 3 cotransporter gene ( SLC4A5 ) on chromosome 2 encodes a protein that transports sodium and bicarbonate across the cell membrane and regulates cellular pH. The National Heart, Lung, and Blood Institute Family Blood Pressure Program found l
Autor:
Kari E. North, Albert Oberman, Laura Almasy, Michael B. Miller, John Blangero, James S. Pankow, Ingrid B. Borecki, Steven C. Hunt, Kathryn M. Rose
Publikováno v:
Hypertension. 43:780-784
Previous analysis in the Hypertension Genetic Epidemiology Network (HyperGEN) of the National Heart Lung and Blood Institute (NHLBI) Family Blood Pressure Program, a multicenter study of genetic and environmental factors related to hypertension, indi
Autor:
Richard S. Cooper, Aravinda Chakravarti, Stephen T. Turner, Ruth Ann Barkley, Michael A. Province, R. Curtis Ellison, Eric Boerwinkle, Steven C. Hunt, Alan B. Weder
Publikováno v:
Hypertension. 43:477-482
Chromosome 2 has been consistently identified as a genomic region with genetic linkage evidence suggesting that one or more loci contributes to blood pressure and hypertension status. As with all complex disease traits, following-up linkage evidence
Autor:
Gordon H. Williams, Roger R. Williams, Richard M. Mortensen, Claudio Ferri, Norman K. Hollenberg, Xavier Jeunemaitre, Paul N. Hopkins, Steven C. Hunt, Natapong Kosachunhanun, Pierre Corvol
Publikováno v:
Hypertension. 42:901-908
We sought to determine whether genes of the renin-angiotensin-aldosterone system can predict the nonmodulating intermediate phenotype in essential hypertension. Aldosterone responses to angiotensin II were assessed in 298 subjects with hypertension.
Autor:
Paul N. Hopkins, Hilary Coon, Richard M. Cawthon, Nicola J. Camp, Steven C. Hunt, Alka Malhotra, Sandra J. Hasstedt
Publikováno v:
Hypertension. 42:322-328
High pulse pressure, a measure of arterial aging, is an important predictor of cardiovascular and general mortality. It has been suggested that the genetic etiology of pulse pressure is the same as systolic blood pressure. We performed a genome-wide,
Autor:
Gerardo Heiss, R. Curtis Ellison, Howard J. Jacob, Ida Chen, Beatriz L. Rodriguez, Thomas Quertermous, Maurita H. Carrejo, John H. Eckfeldt, Koustubh Ranade, Mark Leppert, Donna K. Arnett, C. Charles Gu, Eric Boerwinkle, Aravinda Chakravarti, D. C. Rao, Richard G. Hutchinson, Charles F. Sing, Nicholas J. Schork, Craig L. Hanis, Ingrid B. Borecki, Steven C. Hunt, Stephen C. Mockrin, John S. Grove, Sharon L.R. Kardia, Peter J. Savage, Michael A. Province, Alan B. Weder, C. Andrew Brown, Stephen T. Turner, David Cox, Albert Oberman, Susan Old, Richard S. Cooper, Robert E. Ferrell, Neil Risch, Kamal Masaki, J. David Curb
Publikováno v:
Hypertension. 39:3-9
The Family Blood Pressure Program (FBPP) consists of 4 independently established multicenter networks of investigators who have complementary approaches to the genetics of blood pressure levels and hypertension. The program has recruited participants
Autor:
Steven C. Hunt, Naomi D.L. Fisher, Albert Vuagnat, Gordon H. Williams, Pierre Corvol, Michel Azizi, Xavier Jeunemaitre, Paul N. Hopkins, Mara Giacché
Publikováno v:
Hypertension. 35:710-716
Abstract —The aldosterone response to infused angiotensin II (Ang II) in patients receiving a low-salt diet has been described as an important phenotype for genetic studies on human hypertension. The objectives of the present study were to determin
Autor:
Kelly L. Onions, Steven C. Hunt, Anil G. Menon, Mark Rutkowski, Yan Ru Su, M.C. Reif, Charles A. Klanke
Publikováno v:
Hypertension. 31:1230-1234
Abstract —Increased body mass index (BMI) has been correlated with increased blood pressure in human populations. To examine the role of the leptin gene ( OB ) in essential hypertension in African Americans, we performed affected sib pair analysis