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Autor:
J.-L. Thomas, D. Serfaty, Didier Chassard, Sophie Christin-Maitre, E. Ochsenbein, Nathalie Chabbert-Buffet
Publikováno v:
Human Reproduction. 26:1338-1347
BACKGROUND Nomegestrol acetate/17β-estradiol (NOMAC/E(2)) is a new monophasic oral contraceptive combining NOMAC (2.5 mg), a highly selective progesterone-derived progestogen, with E(2) (1.5 mg), which is structurally identical to endogenous estroge
Autor:
A.M. Salvatierra, Leila Cochon, Vivian Brache, Horacio B. Croxatto, R. Maldonado, D. P. Levy, C. Jesam, E. Gainer
Publikováno v:
Human Reproduction. 25:2256-2263
BACKGROUND: Current methods of hormonal emergency contraception (EC) are ineffective in preventing follicular rupture when administered in the advanced pre-ovulatory phase. This study was designed to determine the capacity of ulipristal acetate (UPA)
Autor:
Sven M. Carlsen, Eszter Vanky
Publikováno v:
Human Reproduction. 25:786-790
Background Polycystic ovary syndrome (PCOS) tends to run in families and excess intrauterine androgen exposure has been suggested as one possible cause of PCOS. We wanted to study the relationship between maternal and offspring sex hormone levels and
Publikováno v:
Human Reproduction. 19:1465-1471
BACKGROUND It has been proposed that hormonal supplementation during prolonged GnRH agonist therapy prevents hypoestrogenic side effects, including bone loss. The optimal combination for long-term treatments with safe metabolic profile remains questi
Publikováno v:
Human Reproduction. 17:589-594
BACKGROUND Phytoestrogens, including genistein and other inhibitors of tyrosine kinases (TKs), inhibit specific steroidogenic enzymes. This study was designed to compare the effects of genistein, with two other TK inhibitors, on steroid synthesis in
Publikováno v:
Human Reproduction. 16:1037-1045
We have compared the oestrogenic potency of the synthetic oestrogen Zeranol, used as a growth promoter in meat production, and five related compounds, with the potency of 17beta-oestradiol, diethylstilboestrol (DES), genistein, and Bisphenol-A. The p
Autor:
Farzad Pakdel, Rémy Le Guével
Publikováno v:
Human Reproduction. 16:1030-1036
Three in-vitro bioassays were used to compare the oestrogenic potency of chemicals used as growth promoter in beef cattle in certain non-European Union countries (17beta-oestradiol, alpha-zearalanol, testosterone, trenbolone, trenbolone acetate, mele
Publikováno v:
Human Reproduction. 13:3009-3015
The purpose of the present study was to investigate a possible participation of the kinin-kallikrein system (KKS) in the pathophysiology of ovarian hyperstimulation syndrome (OHSS). Symptoms of hyperstimulation were produced in immature female rats u
Publikováno v:
Human Reproduction. 12:1903-1908
Human endometrial tissue was collected from 30-37 year old ovulatory women and enzymatically dispersed and processed to obtain endometrial stromal cells. Cells (2 x 10(4)/well) were incubated in vitro in the absence (control) or presence of human cho
Publikováno v:
Human Reproduction. 12:1629-1634
The role of progesterone in capillary permeability, which may be causally related to the pathophysiology of ovarian hyperstimulation syndrome (OHSS), was investigated in immature rats. A total of 96 female Wistar rats aged 22 days were given 10 IU of