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pro vyhledávání: '"11"'
Publikováno v:
Human pathology. 30(7)
Colonic carcinomas with minimal or no glandular differentiation are a heterogeneous group of neoplasms which differ in their histologic appearance, clinical features, prognosis and molecular characteristics. Since 1990, we prospectively identified 11
Autor:
Phyllis C. Huettner, Maureen J. O'Sullivan, Daniela S. Gerhard, Yan Li, Deborah J. Gersell, Kathryn Trinkaus, Janet S. Rader
Publikováno v:
Human Pathology. 32:475-478
We have previously demonstrated a strong relationship between loss of heterozygosity (LOH) at chromosome 11q23.3 and the presence of extensive tumor plugs in lymphvascular spaces (LVS) in stage 1B cervical carcinoma, suggesting that genes at this loc
Publikováno v:
Human pathology. 34(8)
The insulin-like growth factor-1 receptor (IGF1-R) is a cellular receptor overexpressed in many tumor cell lines and in some human tumors that seems to play a critical role in transformation, tumorigenicity, and metastasis. To date, a comprehensive e
Autor:
Christian Brambilla, Marie Helene Laverriere, Elisabeth Brambilla, Gilles Frey, Denis Moro, Nathalie Sturm, Sylvie Lantuejoul
Publikováno v:
Human pathology. 31(4)
Neural cell adhesion molecules (NCAM) are adhesion molecules expressed by neural and neuroendocrine tumors and a few biphasic tumors such as synovialosarcomas and breast phyllode tumors. To investigate NCAM expression in mesotheliomas, we studied 26
Autor:
Osamu Dohi, Kohichiroh Yasui, Tomoko Kitaichi, Kei Terasaki, Kanji Yamaguchi, Yoshio Sumida, Nobuhisa Yamada, Naoto Iwai, Yoshito Itoh, Hironori Mitsuyoshi, Atsushi Umemura, Yuji Naito, Taichiro Nishikawa, Yasuyuki Gen, Yoh Zen, Michihisa Moriguchi, Akira Tomie
Publikováno v:
Human Pathology. 62:134-140
Disrupted cell polarity is a feature of epithelial cancers. The partitioning defective 3 (PAR-3) protein, a key component of the PAR complex that regulates the polarization of cells, is involved in tight junction formation at epithelial cell-cell con
Autor:
Caroline Dutriaux, Charline Caumont, Jean-Philippe Merlio, David Cappellen, Béatrice Vergier, Adeline Furudoï, Christine Merlio, J. F. Goussot, Audrey Gros, Christophe Barberis
Publikováno v:
Human Pathology. 48:167-171
We report here an exceptional pattern of atypical lentiginous melanocytic proliferation within an adenoma, leading to focal lamina propria infiltration and pulmonary metastasis, which was considered as primary colonic mucosal melanoma (MM) in a Cauca
Autor:
Xiaoli Zhou, Mingzhan Du, Lingchuan Guo, Yaohui Wang, Xiangshan Fan, Tianyun Liu, Ling Chen, Yifen Zhang, Yuqing Cheng, Qin Huang, Dan Zhou
Publikováno v:
Human pathology. 83
Clinicopathology and risk factors of lymph node metastasis (LNM) in micropapillary early (pT1) gastric carcinoma (MEGC) remain elusive because of the extreme rarity. In this multicenter study, we investigated 1890 consecutive radical resections of ea
Autor:
Ahrong Kim, Nahmgun Oh, Hong-Jae Jo, Won Young Park, Hyun Sung Kim, Geum Am Song, Do Youn Park, So Jeong Lee, Young Keum Kim
Publikováno v:
Human pathology. 78
Endoscopic resection is widely recognized as a first-line treatment for T1 colorectal cancers (CRC), although additional surgical intervention may be indicated based on the risk of lymph node (LN) metastasis. However, risk factors for LN metastasis i
Autor:
Sharifah Nurain Syed Zanaruddin, Wan Mahadzir Wan Mustafa, A.A.N. Khairul Bariah, Sok Ching Cheong, Shin Hin Lau, S Hamid, Yi-Hsin Yang, Amyza Saleh, Rosnah Binti Zain
Publikováno v:
Human Pathology. 44:417-426
The presence of lymph node (LN) metastasis significantly affects the survival of patients with oral squamous cell carcinoma (OSCC). Successful detection and removal of positive LNs are crucial in the treatment of this disease. Current evaluation meth
Autor:
Aleodor A. Andea, Isam E. Eltoum, Raj Patel, Sanjay Kumar, Selvarangan Ponnazhagan, Patricia DeVilliers, Gene P. Siegal, Darshana Jhala
Publikováno v:
Human Pathology. 41:1405-1412
Merkel cell carcinoma is one of the most aggressive primary cutaneous malignancies. Because some Merkel cell carcinomas express the receptor tyrosine kinase KIT, we aimed to evaluate the correlation of KIT expression with the outcome and the presence