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Autor:
Michael L. Klein, Peter J. Francis, Jurg Ott, Martha Neuringer, N. Landauer, Sara C. Hamon, Jonathan Stoddard, Binoy Appukuttan, Emily Simmons, Betsy Ferguson, J. Timothy Stout
Publikováno v:
Human Molecular Genetics. 17:2673-2680
Age-related macular degeneration (AMD), a complex multigenic disorder and the most common cause of vision loss in the elderly, is associated with polymorphisms in the LOC387715/ARMS2 and HTRA1 genes on 10q26. Like humans, macaque monkeys possess a ma