Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Manal F. Abdelmalek"'
Autor:
Andrew M. Shearer, Yanling Wang, Elizabeth K. Fletcher, Rajashree Rana, Emily S. Michael, Nga Nguyen, Manal F. Abdelmalek, Lidija Covic, Athan Kuliopulos
Publikováno v:
Hepatology (Baltimore, Md.). 76(6)
Insulin resistance and poor glycemic control are key drivers of the development of NAFLD and have recently been shown to be associated with fibrosis progression in NASH. However, the underlying mechanisms involving dysfunctional glucose metabolism an
Autor:
Cynthia D. Guy, Ying Wang, Anna Mae Diehl, Dana Portenier, Dawn Piercy, Matthew J Crowley, Andrea D. Coviello, Anastasia-Stefania Alexopoulos, Ranjan Sudan, Cynthia A. Moylan, Manal F. Abdelmalek, Keri A. Seymour, Ricardo Henao
Publikováno v:
Hepatology (Baltimore, Md.). 74(3)
BACKGROUND AND AIMS Whether glycemic control, as opposed to diabetes status, is associated with the severity of NAFLD is open for study. We aimed to evaluate whether degree of glycemic control in the years preceding liver biopsy predicts the histolog
Autor:
S. Megnien, Mohammad S. Siddiqui, Laurent Castera, Katherine Greene, Veronica Miller, Elmer Schabel, David E. Kleiner, Manal F. Abdelmalek, Arun J. Sanyal, Stephen A. Harrison, Scott L. Friedman, Quentin M. Anstee, Vlad Ratziu, Pierre Bedossa, Brent A. Neuschwander-Tetri, Lara Dimick-Santos
Publikováno v:
Hepatology (Baltimore, Md.)
Nonalcoholic steatohepatitis (NASH) is an important cause of liver-related morbidity and mortality. There are no approved therapies, and the results of clinical trials have been difficult to compare due to inconsistent definitions of relevant disease
Autor:
Cynthia D. Guy, Ayako Suzuki, Herbert Pang, Ju Dong Yang, Alastair D. Smith, Manal F. Abdelmalek, Anna Mae Diehl
Publikováno v:
Hepatology (Baltimore, Md.). 59(4)
Estrogens inhibit stellate cell activation and fibrogenesis. Thus, gender and reproductive states may influence the degree of fibrosis in patients with nonalcoholic steatohepatitis (NASH). To investigate the association between gender, menopause, and
Autor:
Takuji, Ishimoto, Miguel A, Lanaspa, Christopher J, Rivard, Carlos A, Roncal-Jimenez, David J, Orlicky, Christina, Cicerchi, Rachel H, McMahan, Manal F, Abdelmalek, Hugo R, Rosen, Matthew R, Jackman, Paul S, MacLean, Christine P, Diggle, Aruna, Asipu, Shinichiro, Inaba, Tomoki, Kosugi, Waichi, Sato, Shoichi, Maruyama, Laura G, Sánchez-Lozada, Yuri Y, Sautin, James O, Hill, David T, Bonthron, Richard J, Johnson
Publikováno v:
Hepatology (Baltimore, Md.). 58(5)
Fructose intake from added sugars has been implicated as a cause of nonalcoholic fatty liver disease. Here we tested the hypothesis that fructose may interact with a high-fat diet to induce fatty liver, and to determine if this was dependent on a key
Autor:
Manal F, Abdelmalek, Ayako, Suzuki, Cynthia, Guy, Aynur, Unalp-Arida, Ryan, Colvin, Richard J, Johnson, Anna Mae, Diehl, Katherine, Yates
Publikováno v:
Hepatology (Baltimore, Md.). 51(6)
The rising incidence of obesity and diabetes coincides with a marked increase in fructose consumption. Fructose consumption is higher in individuals with nonalcoholic fatty liver disease (NAFLD) than in age-matched and body mass index (BMI)-matched c
Autor:
Manal F. Abdelmalek, Yi Ling Xu, Roniel Cabrera, Haizhen Zhu, Zhengkun Tu, David R. Nelson, Gary L. Davis, Chen Liu, Consuelo Soldevila-Pico
Publikováno v:
Hepatology (Baltimore, Md.). 38(4)
An imbalance in Th1 and Th2 cytokine production is implicated in disease progression of HCV. Our aim was to determine the effect of IL-10 administration in patients with HCV-related liver disease. Thirty patients with advanced fibrosis who had failed