Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter Mohr"'
Publikováno v:
Helvetica Chimica Acta. 64:379-388
The structures 2–5 are assigned to the pseurotin B, C, D and E, which are new metabolites of Pseudeutorium ovalis STOLK, based on spectroscopic data and chemical transformations.
Publikováno v:
Helvetica Chimica Acta. 69:718-725
Changes in chemical shifts of olefinic protons in a number of α,β- and α,β,γ,δ-unsaturated carboxylic acids caused by ionization of the COOH group were investigated. The ionization shifts of α-H-atoms are −0.09 to 0.07 ppm, those of β-H-ato
Publikováno v:
Helvetica Chimica Acta. 66:744-754
Three syntheses of (2S, 3R)-2,5-dihydroxy-3-methylpentanoic acid (verrucarinic acid) and its derivatives suitably protected for the further transformation to macrocyclic trichothecenes are described. These involve an enantioselective ester hydrolysis
Publikováno v:
Helvetica Chimica Acta. 66:2501-2511
Pig liver esterase-(PLE) catalyzed hydrolysis of dimethyl esters of symmetrical dicarboxylic acids, including meso-diacids, cis-1,2-cycloalkanedicarboxylic acids, and diacids with a prochiral center, was studied with 14 substrates. The products of th
Publikováno v:
Helvetica Chimica Acta. 67:1625-1629
Two new syntheses of verrucarinic acid (2S, 3R-dihydroxy-3-methylpentanoic acid) and its derivatives, suitably protected for the further conversion to macrocyclic trichothecenes, are described. The first one makes use of a diastereoselective alkylati
Publikováno v:
Helvetica Chimica Acta. 65:1412-1417
The title compounds have been synthesized starting from verrucarol and diacetoxyscripenol (anguidine), (E, Z)-muconic half ester and a derivative of verrucarinic acid. The latter has been prepared in optically active form from dimethyl 3-methylglutar
Publikováno v:
Helvetica Chimica Acta. 70:142-152
The pH dependence of the α-chymotrypsin-catalyzed hydrolysis of dimethyl 3-hydroxyglutarate (3) has been studied. The e.e. was determined by HPLC analysis of diastereoisomeric camphanoic-acid derivatives. Kinetic resolution of the β,α-epoxy esters