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Autor:
Tony Green, François Delhommeau, Richard A. Van Etten, Danilo Perrotti, Tariq I. Mughal, Ruben A. Mesa, Steffen Koschmieder, Amr R. Ibrahim, Tessa L. Holyoake, John M. Goldman, Animesh Pardanani, Robert Peter Gale
Publikováno v:
Haematologica. 96(4)
This review focuses on topical issues in the biology and treatment of the myeloproliferative neoplasms (MPNs). Studies in transgenic mice suggest that BCR-ABL1 reduces the fraction of self-renewing 'leukemic' stem cells in the bone marrow but that so