Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Susan P. Lees-Miller"'
Autor:
John B. McIntyre, Michelle Dean, Martin Köbel, Tien Phan, Emeka K. Enwere, Elizabeth N. Kornaga, Corinne M. Doll, Prafull Ghatage, Angela Chan, Kevin Martell, Susan P. Lees-Miller
Publikováno v:
Gynecologic Oncology. 158:776-784
Purpose This study aimed to describe the prognostic value of PI3K/AKT pathway mutations in a large cohort of patients with cervical cancer. Experimental design Patients with pre-treatment archival specimens, diagnosed with FIGO stages IB-IVA cervical
Autor:
Jackson S.Y. Wu, Tien Phan, Peter S. Craighead, Martin Köbel, Susan P. Lees-Miller, John B. McIntyre, Anthony M. Magliocco, Corinne M. Doll, Prafull Ghatage
Publikováno v:
Gynecologic oncology. 128(3)
Objective Mutational activation of PIK3CA is associated with poor prognosis in patients with solid tumors, and may predict favorable response to PI3K/AKT/mTOR pathway inhibitors. However, PIK3CA mutational status has not previously been evaluated in