Zobrazeno 1 - 7
of 7
pro vyhledávání: '"J. Carl Barrett"'
Autor:
Zhongwu Lai, Darren Hodgson, Brian Dougherty, J. Carl Barrett, Tsveta Milenkova, Elizabeth A. Harrington, Jessica S Brown, Eric Pujade-Lauraine, Simon Dearden, Alexandra Leary, Jerry S. Lanchbury, Michael C. Perry, Cathy E. Elks, Kirsten Timms
Publikováno v:
Gynecologic oncology. 163(3)
Objective Maintenance olaparib provided a progression-free survival benefit in the phase III SOLO2 trial (NCT01874353) in patients with platinum-sensitive relapsed ovarian cancer and a BRCA mutation (BRCAm). However, questions remain regarding tumor
Publikováno v:
Gynecologic Oncology. 90:123-130
Objective Despite the high prevalence of uterine leiomyoma in women, little is known about the pathophysiology of this tumor. This study intends to define the epigenetic modulation of this tumor. Methods Twenty-three pairs of leiomyomas and their adj
Autor:
Barbara J. Davis, J. Carl Barrett, Julie F. Foley, Cynthia A. Afshari, Xiao-Yu Ding, Christopher D. Houle
Publikováno v:
Gynecologic Oncology. 86:69-78
Objective. Impairment of cell adhesion plays a vital role in tumor progression. E- and N-cadherin, CD9, and KAI1 are all adhesion molecules that have been implicated in the progression of several different tumor types. To help explain the potential r
Autor:
Jennifer Brady, J. Carl Barrett, Martha R. Stampfer, Cynthia A. Afshari, Lori A. Terry, LouAnn Cable, Lois A. Annab
Publikováno v:
Gynecologic Oncology. 77:121-128
Objective. The aim of this study was to examine whether cells containing the heterozygous form of a BRCA1 185delAG mutation would exhibit abnormal growth or an altered response to DNA damage. Methods. A primary culture of human mammary epithelial cel
Publikováno v:
Gynecologic oncology. 92(2)
Objectives . Cyclooxygenase-1 and 2 (COX-1 and COX-2) play important roles in normal physiology and are often dysregulated in neoplastic tissues. The present study determines whether COX-1 and COX-2 are expressed in ovarian cancers and whether the pa
Autor:
G. Larry Maxwell, Betty C. Tong, Heather S. Shaw, John I. Risinger, P. Andrew Futreal, J. Carl Barrett, Andrew Berchuck
Publikováno v:
Gynecologic oncology. 70(1)
Objective. The PTEN tumor suppressor gene on chromosome 10q23 undergoes inactivating mutations in several types of malignancies including glioblastomas and prostate and endometrial carcinomas. The aim of this study was to determine if mutation of the
Autor:
Li S; Laboratory of Women's Health, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., Miner K, Fannin R, Carl Barrett J, Davis BJ
Publikováno v:
Gynecologic oncology [Gynecol Oncol] 2004 Feb; Vol. 92 (2), pp. 622-7.