Zobrazeno 1 - 10
of 844
pro vyhledávání: '"11"'
Autor:
Rachel Cooney, Ajay Verma, John Ramage, Cathryn Edwards, Helen Steed, Evangelos Stournaras, Tim Raine, Charles Murray, Miles Parkes, Alison Simmons
Publikováno v:
Gut
ObjectiveThiopurines are widely used as maintenance therapy in inflammatory bowel disease (IBD) but the evidence base for their use is sparse and their role increasingly questioned. Using the largest series reported to date, we assessed the long-term
Autor:
Hildegard Büning, Xizhong Shen, Amar Deep Sharma, Michael Ott, Taihua Yang, Elmar Jaeckel, Guangqi Song, Tobias Cantz, Anna-Carina Weiss, Qinggong Yuan, Xuemei Jiang, Asha Balakrishnan, Michael Manns, Selina Möbus, Zhen Dai, Martin Bentler, Heike Bantel, Arndt Vogel, Andreas Kispert, Anna Saborowski, Ji-Min Zhu
Publikováno v:
Gut. 69:1104-1115
ObjectiveLiver fibrosis and cirrhosis resulting from chronic liver injury represent a major healthcare burden worldwide. Growth differentiation factor (GDF) 11 has been recently investigated for its role in rejuvenation of ageing organs, but its role
Publikováno v:
Gut. 45(6)
BACKGROUND—Proinflammatory and anti-inflammatory cytokines are involved in the pathogenesis of acute pancreatitis. AIMS—To measure the serial serum levels of interleukin 10 and interleukin 11 in patients with acute pancreatitis and analyse the re
Autor:
Stefan Kubicka, W. Stangel, K Böker, Hans L. Tillmann, Dong-Feng Chen, A. Grundey, A. Berning-Haag, LT Pastucha, V. Kliem, M.P. Manns, Christian Trautwein
Publikováno v:
Gut. 48:714-718
Hepatitis C virus (HCV) infection becomes chronic in more than 70% of patients, leading to end stage liver disease in about 20-30% of these patients. Apart from the virus itself, host factors that modulate the immune response are likely to be involve
Publikováno v:
Gut. 35:101-106
Twelve episodes of acute fatty liver of pregnancy (AFLP) were diagnosed in 11 patients during the past 18 years in a general hospital in Santiago, Chile, with a prevalence of 1 per 15,900 deliveries. Acute fatty liver of pregnancy started between the
Publikováno v:
Gut. 62:A8.1-A8
Introduction Methotrexate (MTX) is used as an immunosuppressive treatment in inflammatory bowel disease (IBD). The aim of the study was to evaluate the long-term tolerability of MTX in adults with IBD from a large, single, tertiary referral centre. M
Publikováno v:
Gut. 63:A102.1-A102
Introduction Oesophagogastroduodenoscopy (OGD) is the investigation of choice for excluding upper gastrointestinal cancer (UGIC). However, published studies suggest 14% of UGIC subjects had an OGD that failed to diagnose cancer in the 3 years prior t
Publikováno v:
Gut. 63:A21.1-A21
Introduction Colonoscopy is the standard of care for diagnosing colorectal cancer (CRC). However, 3.4%–7.9% of subjects with CRC are reportedly diagnosed within 3yrs of a colonoscopy that did not detect the cancer (post-colonoscopy colorectal cance
Autor:
Tatjana Djureinovic, Johanna Skoglund, Lennart Iselius, Jana Vandrovcova, Antonia Kalushkova, Annika Lindblom, Xiao-Lei Zhou
Publikováno v:
Gut. 55:362-366
Background and aim: Known colorectal cancer syndromes, such as familial adenomatous polyposis and hereditary non-polyposis colorectal cancer, have been identified in only a small proportion of cases with a family history of disease. In an attempt to
Autor:
Emmanuelle MASSON, Julia Mayerle, Michael Stumvoll, Sevastita Iordache, Matthias Löhr, Frank Ulrich Weiss, Jochen Hampe, Josefina Mora Brugués, Peter Kovacs, Jian-Min Chen, Anita Gasiorowska, Milena Di Leo, Giulia Martina Cavestro, DAVIDE MARTORANA, Stephen Pereira, Halina Cichoż-Lach, Markus M. Lerch, Ewa Malecka-Wojciesko, Hana Algül, Francisco X Real, Adrian Saftoiu
Publikováno v:
Gut, 64, 9, pp. 1426-33
Gut, 64, 1426-33
Gut, 64, 1426-33
Objective Several genetic risk factors have been identified for non-alcoholic chronic pancreatitis (NACP). A genome-wide association study reported an association of chronic pancreatitis (CP) with variants in PRSS1 – PRSS2 ( rs10273639 ; near the g