Zobrazeno 1 - 10
of 473
pro vyhledávání: ''
Autor:
Yee-Kit Tse, Henry Lik-Yuen Chan, Vincent Wai-Sun Wong, Jinlian Yang, Sally She-Ting Shu, Anthony W.H. Chan, Yan Wang, Xiao-Tang Fan, Grace Lai-Hung Wong, Xieer Liang, Jian Sun, Jinlin Hou, Fang-Ping He
Publikováno v:
Hepatobiliary Surg Nutr
ObjectiveFibrosis stage is strongly associated with liver-related outcomes and is a key surrogate endpoint in drug trials for non-alcoholic steatohepatitis. Dual-photon microscopy allows automated quantification of fibrosis-related parameters (q-FPs)
Autor:
Umang Jain, Chin-Wen Lai, Li Li, Ta-Chiang Liu, Minhu Chen, Brian D. Muegge, Charles E. Whitehurst, Ryan J. Musich, Thaddeus S. Stappenbeck, Shanshan Xiong, Yongjian Liu, Scott T. Espenschied, Gyu Seong Heo
Publikováno v:
Gut. 71(7)
ObjectiveFibrosis is a common feature of Crohn’s disease (CD) which can involve the mesenteric fat. However, the molecular signature of this process remains unclear. Our goal was to define the transcriptional signature of mesenteric fibrosis in CD
Autor:
Emilie Benoit a la Guillaume, Raphael Olivier, Michel Neunlist, Céline Bossard, Jean-François Mosnier, Claude Boccara, Lucille Quénéhervé, Charlène Brochard, Michalina Gora, Emmanuel Coron
Publikováno v:
Gut
Gut, 2020, 70 (1), pp.6-8. ⟨10.1136/gutjnl-2020-321228⟩
Gut, BMJ Publishing Group, 2020, 70 (1), pp.6-8. ⟨10.1136/gutjnl-2020-321228⟩
Gut, 2020, 70 (1), pp.6-8. ⟨10.1136/gutjnl-2020-321228⟩
Gut, BMJ Publishing Group, 2020, 70 (1), pp.6-8. ⟨10.1136/gutjnl-2020-321228⟩
International audience; Full-field optical coherence tomography (FFOCT) is an imaging technique of biological tissue based on tissue light reflectance analysis. We evaluated the feasibility of imaging fresh digestive mucosal biopsies after a quick mo
Autor:
Matías A. Avila, Markus Peck-Radosavljevic, Valérie Paradis, Fabien Zoulim, Jean-Charles Nault, Riad Salem, Jean-François Dufour, Jordi Bruix, Tim F. Greten, Peter R. Galle, Herbert Tilg, Alexander L. Gerbes
Publikováno v:
Gut. 67:380-388
Hepatocellular carcinoma (HCC) ranks number three among the most frequent causes of death from solid tumors worldwide. With obesity and fatty liver diseases as risk factors on the rise, HCC represents an ever increasing challenge. While there is stil
Autor:
Andre Verheem, Szabolcs Fatrai, Tijana Borovski, Susanne J. van Schelven, Inne H.M. Borel Rinkes, Thomas T. Vellinga, Dieuwke Marvin, Onno Kranenburg, Evan E. Santo, Inge Ubink, Jamila Laoukili
Publikováno v:
Gut, 66(6), 1106-1115. BMJ Publishing Group
Background and aim Colorectal cancer (CRC) remains one of the leading causes of cancer-related death. Novel therapeutics are urgently needed, especially for tumours with activating mutations in KRAS (∼40%). Here we investigated the role of RAF1 in
Autor:
Claudia Günther, Kerstin Amann, Stefan Wirtz, Christoph Becker, Gui-Wei He, Christopher Poremba, Markus F. Neurath, Veronika Thonn, Andreas E. Kremer
Publikováno v:
Gut. 66:716-723
Objectives Autoimmune hepatitis (AIH) is a severe necroinflammatory liver disease associated with significant mortality. Although loss of hepatocytes is generally recognised as a key trigger of liver inflammation and liver failure, the regulation of
Autor:
Stephen J. Vanner, Frances Dang, Giada De Palma, K. McIntosh, Premysl Bercik, Ammar Hassanzadeh Keshteli, David E. Reed, Karen L. Madsen, Theresa Schneider
Publikováno v:
Gut. 66:1241-1251
Objective To gain mechanistic insights, we compared effects of low fermentable oligosaccharides, disaccharides and monosaccharides and polyols (FODMAP) and high FODMAP diets on symptoms, the metabolome and the microbiome of patients with IBS. Design
Publikováno v:
Gut
Background Simple and inexpensive non-invasive fibrosis tests are highly needed but have been poorly studied in sub-Saharan Africa. Methods Using liver histology as a gold standard, we developed a novel index using routine laboratory tests to predict
Publikováno v:
Gut. 67(9)
Intraductal papillary mucinous neoplasms (IPMNs) represent the most common cystic preinvasive lesion in the pancreas, which can progress to invasive pancreatic ductal adenocarcinoma (PDAC). Patients with radiological findings consistent with IPMN are
Publikováno v:
Gut. 65:1575-1577
We read with great interest the study by Brooke and colleagues, in which they revealed that a severe hereditary form of peptic ulcer disease known as ‘cryptogenic multifocal ulcerating stenosing enteritis’ is caused by homozygosity for a truncati