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Publikováno v:
Gut.
With interest we read the recent study by Hegyi et al ,1 who established that the risk for developing pancreatitis conferred by a haplotype spanning the trypsin locus (PRSS1–PRSS22 3) is strongly dependent on exogenous factors. Changes in PRSS14 or
Publikováno v:
Gut
The current coronavirus pandemic is an ongoing global health crisis due to covid-19, caused by severe acute respiratory syndrome coronavirus 2. Although covid-19 leads to little or mild flu-like symptoms in the majority of affected patients, the dise
Publikováno v:
Gut. 68(10)
A 27-year-old man was admitted to our department because of persistent symptoms of fever, dyspnoea, dry cough, elevated C reactive protein (CRP) (258 mg/L), leucocytosis (17×109/L), peripheral eosinophilia (29%) and elevated liver enzymes (alanine a
Autor:
Stephen J. Vanner, Frances Dang, Giada De Palma, K. McIntosh, Premysl Bercik, Ammar Hassanzadeh Keshteli, David E. Reed, Karen L. Madsen, Theresa Schneider
Publikováno v:
Gut. 66:1241-1251
Objective To gain mechanistic insights, we compared effects of low fermentable oligosaccharides, disaccharides and monosaccharides and polyols (FODMAP) and high FODMAP diets on symptoms, the metabolome and the microbiome of patients with IBS. Design
Autor:
Erwin Daniel Brenndörfer, Anette Brass, Lars Frelin, Matti Sällberg, Soo Aleman, Johannes G. Bode, Jonas Söderholm
Publikováno v:
Gut. 61:589-596
Background The non-structural (NS) 3/4A protease/helicase of the hepatitis C virus is known to modulate signalling pathways in the infected hepatocyte by cleaving CARD adaptor inducing IFNβ (Cardif), T-cell protein tyrosine phosphatase (TC-PTP) and
Autor:
Walter, Reinisch, Sieglinde, Angelberger, Wolfgang, Petritsch, Olga, Shonova, Milan, Lukas, Simon, Bar-Meir, Alexander, Teml, Elke, Schaeffeler, Matthias, Schwab, Karin, Dilger, Roland, Greinwald, Ralph, Mueller, Eduard F, Stange, Klaus R, Herrlinger, Shmuel, Odes
Publikováno v:
Gut. 59:752-759
The aim of the study was to compare azathioprine versus mesalazine tablets for the prevention of clinical recurrence in patients with postoperative Crohn's disease (CD) with moderate or severe endoscopic recurrence.This was a 1 year, double-blind, do
Autor:
Ingrid Laurendeau, Audrey Sabbagh, Ivan Bièche, Dominique Valla, Marie-Pierre Ripault, Michèle Martinot-Peignoux, Stéphanie Narguet, Patrick Marcellin, Nathalie Boyer, Michel Vidaud, Tarik Asselah
Publikováno v:
Gut. 57:516-524
Background and Aims The gold standard treatment of chronic hepatitis C is the combination of pegylated interferon plus ribavirin. Considering side effects and treatment cost, prediction of treatment response before therapy is important. The aim of ou
Autor:
Federica Benini, M G De Tavonatti, B Panarotto, Ornella Baisini, Francesco Lanzarotto, S Scalia, A. Mora, Alberto Lanzini
Publikováno v:
Gut. 52:1371-1375
Background: Whether ileal absorption of bile acid is up or downregulated in chronic cholestasis is still debated, and most evidence has come from animal studies. Aims: To compare ileal bile acid absorption in patients with primary biliary cirrhosis (
Autor:
Reijo Haapiainen, Pauli Puolakkainen, Jorma Halttunen, V Sainio, U H Stenman, Esko Kemppainen, Eero Kivilaakso, J Hedström
Publikováno v:
Gut. 41:690-695
Aims—To evaluate the clinical utility of two new tests for serum trypsinogen 2 and trypsin 2-α1antitrypsin complex (trypsin 2-AAT) in diagnosing and assessing the severity of acute pancreatitis (AP) induced by endoscopic retrograde cholangiopancre
Publikováno v:
Gut. 40:204-210
BACKGROUND: Acid stable basic fibroblast growth factor (bFGF) promotes angiogenesis and healing of gastric ulcers in rats and reduces subsequent non-steroidal anti-inflammatory drug (NSAID) induced relapse. AIMS: To test in a double blind, placebo co