Zobrazeno 1 - 10
of 21
pro vyhledávání: '"35"'
Autor:
Teruyuki Ueda, Hajime Sunagozaka, Masao Honda, Katsuhisa Horimoto, Shigeru Saito, Shuichi Kaneko, Yoshio Sakai, Sachiyo Aburatani, Hajime Takatori, Mikiko Nakamura, Taro Yamashita
Publikováno v:
Genomics. 101(4):238-248
Background & aims Gene expression profiling of hepatocellular carcinoma (HCC) and background liver has been studied extensively; however, the relationship between the gene expression profiles of different lesions has not been assessed. Methods We exa
Publikováno v:
Genomics. 73:66-76
The expression of ABCA1, a major participant in apolipoprotein-mediated cholesterol efflux, is regulated by a variety of factors, including intracellular cholesterol concentration. To identify sequences involved in its regulation, we sequenced and co
Publikováno v:
Genomics. 70:82-92
We report here the characterization of PSKH1, a novel human protein serine kinase with multiple intracellular localizations. The gene consists of three exons distributed over 35 kb of genomic DNA in region 16q22.1. The 3.4-kb cDNA predicts a protein
Publikováno v:
Genomics. 63:354-373
Five related cytokine genes, interleukin 3 (Il3), interleukin 4 (Il4), interleukin 5 (Il5), interleukin 13 (Il13), and granulocyte-macrophage colony-stimulating factor (Csfgm or Csf2), are tightly linked on mouse chromosome 11. We now describe a 1-Mb
Autor:
Eugene R. Zabarovsky, Dan Grandér, Mats Merup, Gösta Gahrton, Xiushan Wu, Birgitta Stellan, Ganka Ivanova, Monika Jansson, Stefan Einhorn
Publikováno v:
Genomics. 60:161-171
The pathogenesis of hairy cell leukemia (HCL) remains largely unknown since no specific genetic lesion has been identified in this disease. Previous cytogenetic analysis from our group has shown that chromosome abnormalities involving the 5q13 band a
Autor:
Mats Gåfvels, Bhanu P. Chowdhary, Ingemar Björkhem, Monica Jansson, Terje Raudsepp, Ulla Andersson, Bengt Persson, Gösta Eggertsen, Maria Olin
Publikováno v:
Genomics. 56:184-196
Sterol 12alpha-hydroxylase (CYP8B1) is a hepatic cytochrome P-450 that controls the ratio of cholic acid over chenodeoxycholic acid in bile and thus controls the solubility of cholesterol. Both the human and the mouse CYP8B1 complementary DNA and gen
Publikováno v:
Genomics. 52:79-89
The mouse TNFR2 gene has been cloned, sequenced, and characterized as a gene spanning44 kb of the genome. By alignment of five genomic clones we have established that TNFR2 consists of 10 exons and 9 introns with exons ranging in size from 35 bp to 2
Autor:
Kaori Goto, Ayako Ono, Susumu Taguchi, Masaaki Yamazaki, Naomi Yamagata, Asako Ando, Hiroyuki Tashiro, Toshimichi Ikemura, Akira Oka, Lei Chen, Nobuhisa Mizuki, Koji Watanabe, Chiyo Sugawara, Minoru Kimura, Takashi Shiina, Eri Kikkawa, Gen Tamiya, Tetsushi Yamagata, Yasuhito Fukuzumi, Hidetoshi Inoko
Publikováno v:
Genomics. 47:372-382
To elucidate the complete gene structure and to identify new genes involved in the development of HLA class I antigen-associated diseases in the class I region of the human major histocompatibility complex on chromosome 6, a YAC clone (745D12) coveri
Publikováno v:
Genomics. 44:292-299
Overlapping DNA fragments spanning approximately 21 kb of genomic DNA and encompassing the human 4-hydroxyphenylpyruvate dioxygenase gene (HPD) have been cloned by screening a human leukocyte genomic library and by PCR amplification of human fibrobla
Publikováno v:
Genomics. 35:207-214
Analysis of a region of DNA, coamplified in tumors with KRAS2, resulted in the identification of the human homologue of the mouse KRAG gene. The gene was widely expressed in range of cell lines, tumors, and normal tissue and demonstrated a high degre