Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jeremy N. Rich"'
Autor:
Justin D. Lathia, Stephen C. Mack, Claudia L.L. Valentim, Erin E. Mulkearns-Hubert, Jeremy N. Rich
Publikováno v:
Genesdevelopment. 29(12)
Tissues with defined cellular hierarchies in development and homeostasis give rise to tumors with cellular hierarchies, suggesting that tumors recapitulate specific tissues and mimic their origins. Glioblastoma (GBM) is the most prevalent and maligna
Autor:
Diana H. Yan, Jennifer DeVecchio, Qiulian Wu, Kenneth Yan, Anita B. Hjelmeland, Matthew F. Kalady, Jeremy N. Rich, Christine Lee, Isabel Tritschler, Nasiha Rahim
Publikováno v:
Genesdevelopment. 28(10)
Glioblastomas are the most prevalent and lethal primary brain tumor and are comprised of hierarchies with self-renewing cancer stem cells (CSCs) at the apex. Like neural stem cells (NSCs), CSCs reside in functional niches that provide essential cues
Autor:
Robert J. Weil, Anita B. Hjelmeland, Akiko Nishiyama, Masahiro Hitomi, David R. Serwanski, Shideng Bao, Justin D. Lathia, Eunhee Kim, Youngmi Kim, Jeongwu Lee, Olga A. Guryanova, Jeremy N. Rich, Qiulian Wu, Andrew E. Sloan
Publikováno v:
Genesdevelopment. 26(11)
Growth factor-mediated proliferation and self-renewal maintain tissue-specific stem cells and are frequently dysregulated in cancers. Platelet-derived growth factor (PDGF) ligands and receptors (PDGFRs) are commonly overexpressed in gliomas and initi
Autor:
Robert T. Abraham, Nesrin M Hamad, Antoine E. Karnoub, Wenli Bai, Christopher M. Counter, Joel H. Elconin, Jeremy N. Rich, Channing J. Der
Publikováno v:
Genesdevelopment. 16(16)
The spectrum of tumors associated with oncogenic Ras in humans often differs from those in mice either treated with carcinogens or engineered to sporadically express oncogenic Ras, suggesting that the mechanism of Ras transformation may be different