Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
Priya Aggarwal, Douglas I. Lin, Craig H. Bassing, Mariusz A. Wasik, Andrew B. Gladden, Matthew D. Lessie, Laura L. Pontano, Beth Nuskey, J. Alan Diehl, Andres J. Klein-Szanto, Ami Goradia, Anil K. Rustgi
Publikováno v:
Genes & Development. 21:2908-2922
Deregulation of cyclin D1 occurs in numerous human cancers through mutations, alternative splicing, and gene amplification. Although cancer-derived cyclin D1 mutants are potent oncogenes in vitro and in vivo, the mechanisms whereby they contribute to
Autor:
Claudia D. Andl, Anil K. Rustgi, Andres J. Klein-Szanto, Douglas B. Stairs, Jiri Kalabis, Hiroshi Nakagawa, Cameron N. Johnstone, Wafik S. El-Deiry, Takaomi Okawa, Edna Cukierman, Carmen Z. Michaylira, Meenhard Herlyn
Publikováno v:
Genes & Development. 21:2788-2803
Esophageal cancer is a prototypic squamous cell cancer that carries a poor prognosis, primarily due to presentation at advanced stages. We used human esophageal epithelial cells as a platform to recapitulate esophageal squamous cell cancer, thereby p