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Publikováno v:
Genes
Genes, Vol 11, Iss 1528, p 1528 (2020)
Genes, Vol 11, Iss 1528, p 1528 (2020)
Fanconi anemia (FA), a chromosomal instability syndrome, is caused by inherited pathogenic variants in any of 22 FANC genes, that cooperate in the FA/BRCA pathway. This pathway regulates the repair of DNA interstrand crosslinks (ICLs) through homolog