Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Manal F. Abdelmalek"'
Publikováno v:
Gastroenterology. 163:e10-e12
Autor:
Robert H. Eckel, Leon A. Adams, Christos S. Mantzoros, Kenneth Cusi, Stephen A. Harrison, Fasiha Kanwal, Eugene E. Wright, Vincent Wai-Sun Wong, Hashem B. El-Serag, Rohit Loomba, Elisabetta Bugianesi, Manal F. Abdelmalek, Lee M. Kaplan, Kim Pfotenhauer, Jay H. Shubrook
Publikováno v:
Gastroenterology, vol 161, iss 5
Gastroenterology
Gastroenterology
Find AGA's NASH Clinical Care Pathway Appfor iOS and Android mobile devices at nash.gastro.org. Scan this QR code to be taken directly to the website.Nonalcoholic fatty liver disease (NAFLD) is becoming increasingly common, currently affecting approx
Autor:
B. Mccolgan, Eric Lawitz, Anna Mae Diehl, Catherine Jia, Manal F. Abdelmalek, Jaime Bosch, Zobair M. Younossi, G. Mani Subramanian, Mitchell L. Shiffman, John G. McHutchison, Reem Ghalib, Nezam H. Afdhal, Don C. Rockey, Andrew J. Muir, Raul Aguilar Schall, Vlad Ratziu, Zachary Goodman, Stephen H. Caldwell, Arun J. Sanyal, Stephen A. Harrison, Robert P. Myers
Publikováno v:
Gastroenterology. 155:1140-1153
Background & Aims Lysyl oxidase-like 2 contributes to fibrogenesis by catalyzing cross-linkage of collagen. We evaluated the safety and efficacy of simtuzumab, a monoclonal antibody against lysyl oxidase-like 2, in two phase 2b trials of patients wit
Autor:
Andrea G. Nackley, Wolfgang Liedtke, Anna Mae Diehl, Huiping Ding, Andreas E. Kremer, Johannes Morstein, Ana E. López-Romero, Qian Zeng, Zilong Wang, Ru-Rong Ji, Qiaojuan Zhang, Yong Chen, Xin Zhang, Piotr Milkiewicz, Tony E. Reeves, Sara L. Morales-Lázaro, Jennifer Y. Zhang, Marcin Krawczyk, Tamara Rosenbaum, Mei-Chuan Ko, Frank Lammert, Andrey V. Bortsov, Manal F. Abdelmalek, Michele Yeo, Huanghe Yang, Carlene Moore, Ying-Ai Jin
Publikováno v:
Gastroenterology. 161(1)
Background & Aims Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of antipruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus. Meth
Autor:
Naga Chalasani, Manal F. Abdelmalek, Guadalupe Garcia-Tsao, Raj Vuppalanchi, Naim Alkhouri, Mary Rinella, Mazen Noureddin, Maxmillan Pyko, Mitchell Shiffman, Arun Sanyal, Adam Allgood, Harold Shlevin, Rex Horton, Eliezer Zomer, William Irish, Zachary Goodman, Stephen A. Harrison, Peter G. Traber, Manal Abdelmalek, Luis Balart, Brian Borg, Michael Charlton, Hari Conjeevaram, Michael Fuchs, Reem Ghalib, Pierre Gholam, Dina Halegoua-De Marzio, Stephen Harrison, Christopher Jue, Nyingi Kemmer, Kris Kowdley, Michelle Lai, Eric Lawitz, Rohit Loomba, Angelo Paredes, Don Rockey, Miguel Rodriguez, Raymond Rubin, Michael Ryan, Andrew Scanga, Thomas Sepe, Brent Tetri, Paul Thuluvath, Dawn Torres, John Vierling, Julia Wattacheril, Amanda Weiland, Donald Zogg
Publikováno v:
Gastroenterology. 158(5)
Background & Aims Increased levels of galectin 3 have been associated with nonalcoholic steatohepatitis (NASH) and contribute to toxin-induced liver fibrosis in mice. GR-MD-02 (belapectin) is an inhibitor of galectin 3 that reduces liver fibrosis and
Autor:
Jose Luis Calleja, Eric Lawitz, Jean-François Dufour, Martin Bonacci, Salvatore Petta, Michael Allison, Mary E. Rinella, Philippe Mathurin, Lixia Wang, Syed Q. Hussaini, Arun J. Sanyal, Aldo Trylesinki, Luna Zaru, Leigh MacConell, Paul Marotta, Vlad Ratziu, Rodolphe Anty, Reshma Shringarpure, Ingolf Schiefke, Manal F. Abdelmalek, Kris V. Kowdley, Bruce Wong, Quentin M. Anstee
Publikováno v:
Gastroenterology. 158:S-1406
In the REGENERATE interim analysis, obeticholic acid (OCA) improved liver histology in patients with non-alcoholic steatohepatitis (NASH). Elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels may be associated with fibr
Autor:
Grace S. Park, Manal F. Abdelmalek, Karen Lai, Gerardo Rodriguez, Jérôme Boursier, Sven Francque, Naim Alkhouri, Sam E. Moussa, Eduardo B. Martins, Ziad Younes, Alexander Hodge
Publikováno v:
Gastroenterology. 158:S-1446
Autor:
Zac Anchi Chang, Claude B. Sirlin, Benjamin Wildman-Tobriner, Stephen J. Rossi, Manal F. Abdelmalek, Mustafa R. Bashir, Cynthia A. Moylan, Michael M. Middleton, Omar Flores
Publikováno v:
Gastroenterology. 155(5)
BACKGROUND & AIMS: Patients with nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH) often require histologic assessment via liver biopsy. Magnetic resonance imaging (MRI)-based methods for measuring liver triglycerides ba
Autor:
Jeongeun Hyun, Carole Grenier, Anna Mae Diehl, Cynthia A. Moylan, Kuo Du, Ricardo Henao, Manal F. Abdelmalek, Susan K. Murphy
Publikováno v:
Gastroenterology. 156:S-1360
Autor:
Manal F. Abdelmalek, Ricardo Henao, Kara Wegermann, Anna Mae Diehl, Cynthia A. Moylan, Catherine F. Howe, Ying Wang
Publikováno v:
Gastroenterology. 156:S-1223