Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
B. Mccolgan, Eric Lawitz, Anna Mae Diehl, Catherine Jia, Manal F. Abdelmalek, Jaime Bosch, Zobair M. Younossi, G. Mani Subramanian, Mitchell L. Shiffman, John G. McHutchison, Reem Ghalib, Nezam H. Afdhal, Don C. Rockey, Andrew J. Muir, Raul Aguilar Schall, Vlad Ratziu, Zachary Goodman, Stephen H. Caldwell, Arun J. Sanyal, Stephen A. Harrison, Robert P. Myers
Publikováno v:
Gastroenterology. 155:1140-1153
Background & Aims Lysyl oxidase-like 2 contributes to fibrogenesis by catalyzing cross-linkage of collagen. We evaluated the safety and efficacy of simtuzumab, a monoclonal antibody against lysyl oxidase-like 2, in two phase 2b trials of patients wit
Autor:
Andrea G. Nackley, Wolfgang Liedtke, Anna Mae Diehl, Huiping Ding, Andreas E. Kremer, Johannes Morstein, Ana E. López-Romero, Qian Zeng, Zilong Wang, Ru-Rong Ji, Qiaojuan Zhang, Yong Chen, Xin Zhang, Piotr Milkiewicz, Tony E. Reeves, Sara L. Morales-Lázaro, Jennifer Y. Zhang, Marcin Krawczyk, Tamara Rosenbaum, Mei-Chuan Ko, Frank Lammert, Andrey V. Bortsov, Manal F. Abdelmalek, Michele Yeo, Huanghe Yang, Carlene Moore, Ying-Ai Jin
Publikováno v:
Gastroenterology. 161(1)
Background & Aims Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of antipruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus. Meth
Autor:
Steve S. Choi, Jeongeun Hyun, Marzena Swiderska-Syn, Richard T. Premont, Youngmi Jung, Anna Mae Diehl, Bahar Salimian Rizi, George D. Dalton, Kuo Du, Gregory A. Michelotti, Eric Thelen
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Cirrhosis results from accumulation of myofibroblasts derived from quiescent hepatic stellate cells (Q-HSCs); it regresses when myofibroblastic HSCs are depleted. Hedgehog signaling promotes transdifferentiation of HSCs by activatin
Autor:
Jeongeun Hyun, Carole Grenier, Anna Mae Diehl, Cynthia A. Moylan, Kuo Du, Ricardo Henao, Manal F. Abdelmalek, Susan K. Murphy
Publikováno v:
Gastroenterology. 156:S-1360
Autor:
Manal F. Abdelmalek, Ricardo Henao, Kara Wegermann, Anna Mae Diehl, Cynthia A. Moylan, Catherine F. Howe, Ying Wang
Publikováno v:
Gastroenterology. 156:S-1223
Autor:
Elizabeth M. Brunt, Zobair M. Younossi, Anna Mae Diehl, Naga Chalasani, Kenneth Cusi, Joel E. Lavine, Michael Charlton, Arun J. Sanyal
Publikováno v:
Gastroenterology. 142:1592-1609
Publikováno v:
Gastroenterology. 150(8)
Nonalcoholic steatohepatitis (NASH) is a necro-inflammatory response that ensues when hepatocytes are injured by lipids (lipotoxicity). NASH is a potential outcome of nonalcoholic fatty liver (NAFL), a condition that occurs when lipids accumulate in
Autor:
Giraldo Ricardo Henao, Manal F. Abdelmalek, Cynthia A. Moylan, Anna Mae Diehl, Susan K. Murphy
Publikováno v:
Gastroenterology. 152:S1069-S1070
Autor:
Seh-Hoon Oh, Rolf Gebhardt, Bianca Loeffler, Madlen Matz, George D. Dalton, Richard T. Premont, Anna Mae Diehl
Publikováno v:
Gastroenterology. 154:S-166
Publikováno v:
Gastroenterology. 154:S-7