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The Role of Ferroptosis in Bronchoalveolar Epithelial Cell Injury Induced by Cigarette Smoke Extract
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology
Background: Cigarette smoking is a major risk factor for bronchoalveolar epithelial cell (BAEC) injury. Understanding the relevant pathogenesis is important for the treatment of cigarette smoke–related chronic airway diseases such as chronic obstru
Autor:
Laura S. Vasquez-Bolanos, Michael C. Gibbons, Severin Ruoss, Isabella T. Wu, Mario Vargas-Vila, Sydnee A. Hyman, Mary C. Esparza, Donald C. Fithian, John G. Lane, Anshuman Singh, Chanond A. Nasamran, Kathleen M. Fisch, Samuel R. Ward
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology
Rotator cuff (RC) tears are prevalent in the population above the age of 60. The disease progression leads to muscle atrophy, fibrosis, and fatty infiltration in the chronic state, which is not improved with intervention or surgical repair. This high
Autor:
Ming Kong, Mengna Kang, Shangshang Ma, Qi Ge, Qin Yao, Lanlan Liu, Keping Chen, Fan Feng, Shu Zhang, Yanhua Yang, Liang Chen, Min Tang, Lu Gao, Peng Lv
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology
Frontiers in Physiology
The pathogenesis of diabetes mellitus is a complicated process involving much gene regulation. The molecular mechanism of mulberry (Morus alba L.) leaf in the treatment of diabetes is not fully understood. In this study, we used the Illumina HiSeq™
Autor:
Lars Verschuren, Robert Kleemann, Roeland Hanemaaijer, Arianne van Koppen, Martine C. Morrison
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: It is generally accepted that metabolic inflammation in the liver is an important driver of disease progression in NASH and associated matrix remodeling/fibrosis. However, the exact molecular inflammatory mechanisms are poorly defined i
Publikováno v:
Frontiers in Physiology, Vol 4 (2014)
Frontiers in Physiology
Frontiers in Physiology
The Cl(-)/HCO(-) 3anion exchanger 2 (AE2) is known to be involved in intracellular pH (pHi) regulation and transepithelial acid-base transport. Early studies showed that AE2 gene expression is reduced in liver biopsies and blood mononuclear cells fro