Zobrazeno 1 - 3
of 3
pro vyhledávání: '"William R. Wilson"'
Autor:
Cho R. Hong, Gib Bogle, Jingli Wang, Kashyap Patel, Frederik B. Pruijn, William R. Wilson, Kevin O. Hicks
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Intra-tumor heterogeneity represents a major barrier to anti-cancer therapies. One strategy to minimize this limitation relies on bystander effects via diffusion of cytotoxins from targeted cells. Hypoxia-activated prodrugs (HAPs) have the potential
Externí odkaz:
https://doaj.org/article/764b9ed66dd64296903affcf0c72e274
Autor:
Yongchuan Gu, Tony T.-A. Chang, Jingli Wang, Jagdish K. Jaiswal, David Edwards, Noel J. Downes, H. D. Sarath Liyanage, Courtney R. H. Lynch, Frederik B. Pruijn, Anthony J. R. Hickey, Michael P. Hay, William R. Wilson, Kevin O. Hicks
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
3-(3-Morpholinopropyl)-7,8-dihydro-6H-indeno[5,6-e][1,2,4]triazine 1,4-dioxide (SN30- 000), an analog of the well-studied bioreductive prodrug tirapazamine (TPZ), has improved activity against hypoxic cells in tumor xenografts. However, little is kno
Externí odkaz:
https://doaj.org/article/61f746173a7f46688ef3bd8d99214fa6
Autor:
Anthony J. R. Hickey, William R. Wilson, David A. Edwards, Jagdish K. Jaiswal, Kevin O. Hicks, Jingli Wang, Noel J. Downes, Michael P. Hay, H. D. Sarath Liyanage, Tony T.-A. Chang, Courtney R. H. Lynch, Frederik B. Pruijn, Yongchuan Gu
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Frontiers in Pharmacology
Frontiers in Pharmacology
3-(3-Morpholinopropyl)-7,8-dihydro-6H-indeno[5,6-e][1,2,4]triazine 1,4-dioxide (SN30- 000), an analog of the well-studied bioreductive prodrug tirapazamine (TPZ), has improved activity against hypoxic cells in tumor xenografts. However, little is kno