Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ming J"'
Autor:
Nathan D. Seligson, Xunjie Zhang, Mark C. Zemanek, Jasmine A. Johnson, Zachary VanGundy, Danxin Wang, Mitch A. Phelps, Julianna Roddy, Craig C. Hofmeister, Junan Li, Ming J. Poi
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Introduction: Polymorphisms in genes responsible for the metabolism and transport of tacrolimus have been demonstrated to influence clinical outcomes for patients following allogeneic hematologic stem cell transplant (allo-HSCT). However, the clinica
Externí odkaz:
https://doaj.org/article/74d23d0d6a3644e1ac4dd5f599fa8963
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Seligson, Nathan D., Xunjie Zhang, Zemanek, Mark C., Johnson, Jasmine A., VanGundy, Zachary, Danxin Wang, Phelps, Mitch A., Roddy, Julianna, Hofmeister, Craig C., Junan Li, Poi, Ming J.
Publikováno v:
Frontiers in Pharmacology; 2024, p1-10, 10p
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Lung cancer is one of the most common malignant tumors, with the highest mortality rate in the world, and its incidence is second only to breast cancer. It has posed a serious threat to human health. Cisplatin, a metal-based drug, is one of the most
Externí odkaz:
https://doaj.org/article/98d0dd38801148afac5846871b7847b2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Tingting Du, Zhihui Zhang, Jie Zhou, Li Sheng, Haiping Yao, Ming Ji, Bailing Xu, Xiaoguang Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
PARP inhibitors have clinically demonstrated good antitumor activity in patients with BRCA mutations. Here, we described YHP-836, a novel PARP inhibitor, YHP-836 demonstrated excellent inhibitory activity for both PARP1 and PARP2 enzymes. It also all
Externí odkaz:
https://doaj.org/article/92e17dc392634eca811e8d81a769ae31
Autor:
Ming Ji, Zhihui Zhang, Songwen Lin, Chunyang Wang, Jing Jin, Nina Xue, Heng Xu, Xiaoguang Chen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Glioblastoma multiforme (GBM) is the most common malignant tumor of the central nervous system. Temozolomide (TMZ)–based adjuvant treatment has improved overall survival, but clinical outcomes remain poor; TMZ resistance is one of the main reasons
Externí odkaz:
https://doaj.org/article/59f6de3fccf24808aa6aaf913c3d6154
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Purpose: To investigate the efficacy and mechanism of compound 23, a PI3K/HDAC dual-target inhibitor, on hematologic tumor cells in vitro and in vivo. Methods: The MTS Kit was used to study the antiproliferative effects in vitro. Western blot was use
Externí odkaz:
https://doaj.org/article/f719d2bad4184f0cb36ce4d40c13948d
Autor:
Ruyi Li, Peng Song, Guofang Tang, Jianghong Wei, Lizong Rao, Libing Ma, Ming Jiang, Jianwei Huang, Qing Xu, Jingjie Wu, Qian Lv, Dong Yao, Bo Xiao, Haiming Huang, Liping Lei, Juntao Feng, Biwen Mo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Inhibition of activated macrophages is an alternative therapeutic strategy for asthma. We investigated whether a coumarin compound, osthole, isolated from Cnidiummonnieri (L.) Cuss, alleviated macrophage activation in vivo and in vitro. Osthole could
Externí odkaz:
https://doaj.org/article/82c61541fada40b7bb2ae350591a2469
Autor:
Jing Jin, Ming Ji, Rong Fu, Mingjin Wang, Nina Xue, Qiong Xiao, Jingpin Hu, Xiaojian Wang, Fangfang Lai, Dali Yin, Xiaoguang Chen
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Sphingosine-1-phosphate receptor subtype 1 (S1P1) is essential for lymphocyte egress from lymphoid organs into systemic circulation and provides a well-defined drug target for autoimmune disorders. IMMH001, also called SYL930, is a specific S1P1/S1P4
Externí odkaz:
https://doaj.org/article/d269121f3f2944128c35605eacc26f31