Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Lin ZH"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundPain is a complex perception involving unpleasant somatosensory and emotional experiences. However, the underlying mechanisms that mediate its different components remain unclear. Sphingosine-1-phosphate (S1P), a metabolite of sphingomyelin
Externí odkaz:
https://doaj.org/article/4ed8aa86b88e49b597df966c1768e72a
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundPolatuzumab vedotin, the first FDA-approved antibody-drug conjugate (ADC) targeting CD79b, is utilized in the treatment of previously untreated diffuse large B-cell lymphoma (DLBCL) or high-grade B-cell lymphoma (HGBL), as well as relapsed
Externí odkaz:
https://doaj.org/article/8ee67c8af8764e5fb08c2512c0d2b031
Autor:
Lin Zhang, Han Li, Lihan Hu, Xiangqin Ou, Hanzhi Tan, Xuanqi Zhang, Chung Tai Lau, Aiping Lyu, Zhaoxiang Bian, Xuan Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectivesThe impact of the Standard Protocol Items: Recommendations for Interventional Trials of Traditional Chinese Medicine (SPIRIT-TCM) Extension 2018 statement on the reporting quality of randomized controlled trial (RCT) protocols in traditiona
Externí odkaz:
https://doaj.org/article/c2b8971e34c44b4eb14f3a30f53cb038
Autor:
Xiaoqi Liu, Hai Xiao, Mingxia Luo, Junpeng Meng, Lin Zhong, Tao Wu, Yongxia Zhao, Faming Wu, Jian Xie
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction:P. candolleana Wight et Arn. Is a traditional Chinese herbal medicine used by the Gelao nationality in southwest China, has been historically applied to treat various gastrointestinal disorders. Despite its traditional usage, scientific
Externí odkaz:
https://doaj.org/article/c30c44e5db8e4e6c8442c6ea6c333379
Autor:
Bo Chen, Xinqian Dong, Jin Long Zhang, Xitong Sun, Lin Zhou, Kangning Zhao, Hualiang Deng, Zhen Sun
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ulcerative colitis (UC) is a nonspecific inflammatory bowel disease characterized by abdominal pain, bloody diarrhea, weight loss, and colon shortening. However, UC is difficult to cure due to its high drug resistance rate and easy recurrence. Moreov
Externí odkaz:
https://doaj.org/article/7221c888ad484759a54afaae28df98ac
Autor:
Juan Zeng, Bing Leng, Xiaoyan Guan, Shuangyan Jiang, Maoyu Xie, Wenying Zhu, Yue Tang, Lin Zhang, Jing Sha, Tengfei Wang, Min Ding, Nan Guo, Jinjiao Jiang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Elderly patients are more prone to develop acute kidney injury during infections and polymyxin B (PMB)-associated nephrotoxicity than young patients. The differential response to PMB between the elderly and young critically ill patients
Externí odkaz:
https://doaj.org/article/486c81e9a0ed441d913af294faea7a33
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Objectives: Nadroparin, a low-molecular-weight-heparin is commonly used off-label in neonates and infants for thromboembolic events prevention. However, the recommended dosing regimen often fails to achieve therapeutic target ranges. This study aimed
Externí odkaz:
https://doaj.org/article/7ac517f526904735857819f7a5bd20cc
Autor:
Lin Zhao, Jiamei Chen, Bai Bai, Guili Song, Jingwen Zhang, Han Yu, Shiwei Huang, Zhang Wang, Guanghua Lu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Topical drug delivery is widely used in various diseases because of the advantages of not passing through the gastrointestinal tract, avoiding gastrointestinal irritation and hepatic first-pass effect, and reaching the lesion directly to reduce unnec
Externí odkaz:
https://doaj.org/article/e752b1ea6aeb499299afd906e9a9b4ac
Autor:
Lin Zhou, Hongyu Zhang, Shuyi Wang, Hong Zhao, Yongnan Li, Juqian Han, Hongxu Zhang, Xiaoyuan Li, Zhengyi Qu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Ischemic stroke, the most prevalent and serious manifestation of cerebrovascular disease, is the main cause of neurological problems that require hospitalization, resulting in disability and death worldwide. Currently, clinical practice focuses on th
Externí odkaz:
https://doaj.org/article/ef8c0dbb0e16478b9ebe4286e7a49c60
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objective: While several drugs have been linked to acute pancreatitis (AP), the AP-related risk of most drugs remains unclear. This study investigated the risk factors for drug-induced AP by analyzing a large dataset from the FDA Adverse Event Report
Externí odkaz:
https://doaj.org/article/57551c8025894f42824432e68a8f0f32