Zobrazeno 11 - 20
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Autor:
Esperanza Herradón, Cristina González, Antonio González, Jose Antonio Uranga, Visitación López-Miranda
Publikováno v:
Frontiers in Pharmacology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Pharmacology, Vol 12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Pharmacology, Vol 12 (2021)
Vincristine is an effective anticancer agent for treating leukemias, lymphomas, and other solid tumors. Vincristine’s better-known severe side effects include bone marrow depression, hyponatremia, peripheral neuropathy, and gastrointestinal distres
Autor:
Chuang Xiao, Sha Cheng, Zifeng Yang, Rong Huang, Yutao Wang, Deyou Zeng, Hanxiao Pan, Yan Fang, Rongping Zhang, Chen Chen, Haiming Jiang, Weimin Yang, Runfeng Li, Xinhua Wang, Li Xian, Yaping Liang, Xiao Wu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Chronic obstructive pulmonary disease (COPD), a major cause of morbidity and mortality worldwide, is widely considered to be related to cigarette smoke (CS), and viral infections trigger acute exacerbation of COPD (AECOPD). Isoforskolin (ISOF) is a b
Autor:
Zhen Huang, Hui Chen, Shenglin Wang, Hongxiang Wei, Xinwen Wang, Rongkai Shen, Yunqing Wang, Rongjin Lin, Jianhua Lin
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Despite the development of diagnostic and treatment strategies, the survival outcome of patients with osteosarcoma remains poor. Nod-like receptor protein 3 (NLRP3) plays a crucial role in the inflammasome pathway, which is related to the progression
Autor:
Jiarong Wang, Wei Jiang, Jiao Xin, Weiju Xue, Congjian Shi, Jiagen Wen, Yan Huang, Chengmu Hu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Non-alcoholic fatty liver disease (NAFLD) is an independent risk factor for acute liver injury caused by overuse of acetaminophen (APAP). Caveolin-1 (CAV1), a regulator of hepatic energy metabolism and oxidative stress, was found to have a protective
Autor:
Isaac Tabiri Henneh, Ernest Obese, Elvis Ofori Ameyaw, Emmanuel A. Adakudugu, Francis Ackah Armah, Martins Ekor, Robert Peter Biney, Eric Boakye-Gyasi
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
The diversity offered by natural products has timelessly positioned them as a good source for novel therapeutics for the management of diverse medical conditions, including pain. This study evaluated hydro-ethanolic root bark extract of Ziziphus abys
Autor:
Yuan-Li Chen, Yi-Cheng Ma, Cheng-Gang Zou, Guangyu Pu, Shi Chunjing, Dan Zhang, Deng Yi, Jianjun Liu, Lanqing Ma, Ying Yunyan, Miao Yinglei, Bo Zhou, Mingke Li, Daiyan Wen, Yu Wen, Sufeng Luo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Nonalcoholic fatty liver disease (NAFLD) results from an abnormal accumulation of lipids within hepatocytes, and is commonly associated with obesity, insulin resistance, and hyperlipidemia. Metformin is commonly used to treat type 2 diabetes mellitus
Autor:
Defang Li, Qiusheng Zheng, Chongxu Wang, Zhuien Wang, Yao Qin, Wenjuan Xu, Yanwei Yu, Yi Yang, Chendong Yang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Inflammatory bowel disease (IBD) is an important high-risk factor that promotes the occurrence and development of colon cancer. Research on the mechanism of regulating NLRP3 can provide potential targets for treating NLRP3 inflammasome–related dise
Autor:
Alexandre Todorovic Fabro, Tales Rubens de Nadai, Gustavo Urbano, Sabrina Setembre Batah, Patricia de Carvalho Mastroianni, Marcela Forgerini
Publikováno v:
Frontiers in Pharmacology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Pharmacology, Vol 12 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Pharmacology, Vol 12 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Objective: To assess the association between PTGS1 and NOS3 variant alleles and the risk to develop upper gastrointestinal bleeding (UGIB) secondary to complicated peptic disease.Methods: A case–control study was conducted in a Brazilian complex ho
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Intervertebral disc degeneration (IDD) is related to the deterioration of nucleus pulposus (NP) cells due to hypertrophic differentiation and calcification. The imbalance of pro-inflammatory (M1 type) and anti-inflammatory (M2 type) macrophages contr
Autor:
Bo-Wei Wang, Chih-Hao Huang, Liang-Chih Liu, Fang-Ju Cheng, Ya-Ling Wei, Yueh-Ming Lin, Yu-Fei Wang, Ching-Ting Wei, Yeh Chen, Yun-Ju Chen, Wei-Chien Huang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
The proviral integration site for moloney murine leukemia virus 1 (Pim1) is a serine/threonine kinase and able to promote cell proliferation, survival and drug resistance. Overexpression of Pim1 has been observed in many cancer types and is associate