Zobrazeno 1 - 5
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pro vyhledávání: '"Crystal L Mackall"'
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
Technological advances now allow us to rapidly produce CARs and other antibody-derived therapeutics targeting cell surface receptors. To maximize the potential of these new technologies, relevant extracellular targets must be identified. The Pediatri
Externí odkaz:
https://doaj.org/article/f4780f8e34dd424a96ef8606df1e1ed0
Autor:
Rimas J. Orentas, Terry J. Fry, Jianbin He, Sivasish Sindiri, Crystal L. Mackall, Javed Khan, Jessica Nordlund
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 4 (2014)
Frontiers in Oncology, Vol 4 (2014)
Pediatric lymphoid leukemia has the highest cure rate of all pediatric malignancies, yet due to its prevalence, still accounts for the majority of childhood cancer deaths and requires long-term highly toxic therapy. The ability to target B-cell ALL w
Publikováno v:
Frontiers in Oncology
Technological advances now allow us to rapidly produce CARs and other antibody-derived therapeutics targeting cell surface receptors. To maximize the potential of these new technologies, relevant extracellular targets must be identified. The Pediatri
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 2 (2012)
Frontiers in Oncology, Vol 2 (2012)
Immunotherapy for cancer has shown increasing success and there is ample evidence to expect that progress gleaned in immune targeting of adult tumors can be translated into pediatric oncology. Herein we review first the principles that guide selectio
Autor:
Crystal L. Mackall
Publikováno v:
Frontiers in Oncology, Vol 1 (2011)
Frontiers in Oncology
Frontiers in Oncology
Progress made in the battle to cure childhood cancer is one of the great success stories of modern medicine. Some diseases that were universally fatal 50 years ago, such as pediatric acute lymphoblastic leukemia, can now be cured in approximately 80%