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Rare variants and HLA haplotypes associated in patients with neuromyelitis optica spectrum disorders
Autor:
Inna Tabansky, Akemi J. Tanaka, Jiayao Wang, Guanglan Zhang, Irena Dujmovic, Simone Mader, Venkatesh Jeganathan, Tracey DeAngelis, Michael Funaro, Asaff Harel, Mark Messina, Maya Shabbir, Vishaan Nursey, William DeGouvia, Micheline Laurent, Karen Blitz, Peter Jindra, Mark Gudesblatt, Regeneron Genetics Center, Alejandra King, Jelena Drulovic, Edmond Yunis, Vladimir Brusic, Yufeng Shen, Derin B. Keskin, Souhel Najjar, Joel N. H. Stern
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neuromyelitis optica spectrum disorders (NMOSD) are rare, debilitating autoimmune diseases of the central nervous system. Many NMOSD patients have antibodies to Aquaporin-4 (AQP4). Prior studies show associations of NMOSD with individual Human Leukoc
Externí odkaz:
https://doaj.org/article/0949e2708c71481fbc1c38c531d3cb15
Autor:
Tabansky I; Department of Neurology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Urology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Molecular Medicine, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Science Education, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States.; Department of Neurobiology and Behavior, The Rockefeller University, New York, NY, United States., Tanaka AJ; Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, United States., Wang J; Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, United States.; Department of Biomedical Informatics and Department of Systems Biology, Columbia University, New York, NY, United States., Zhang G; Department of Computer Science, Boston University, Boston, MA, United States., Dujmovic I; Clinical Center of Serbia University School of Medicine, Belgrade, Serbia.; Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, United States., Mader S; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States.; Biomedical Center and University Hospitals, Ludwig Maximilian University Munich, Munich, Germany., Jeganathan V; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States., DeAngelis T; Department of Neurology, Neurological Associates of Long Island, New Hyde Park, NY, United States., Funaro M; Department of Neurology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Urology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Molecular Medicine, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Science Education, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States., Harel A; Department of Neurology, Lenox Hill Hospital, Northwell Health, New York, NY, United States., Messina M; Department of Neurology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Urology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Molecular Medicine, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Science Education, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States., Shabbir M; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States., Nursey V; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States., DeGouvia W; Department of Neurology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Urology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Molecular Medicine, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Science Education, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States., Laurent M; Department of Neurology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Urology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Molecular Medicine, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Science Education, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States., Blitz K; Department of Neurology, South Shore Neurologic Associates, Patchogue, NY, United States., Jindra P; Division of Abdominal Transplantation, Baylor College of Medicine, Baylor College of Medicine, Houston, TX, United States., Gudesblatt M; Biomedical Center and University Hospitals, Ludwig Maximilian University Munich, Munich, Germany., King A; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY, United States., Drulovic J; Clinical Center of Serbia University School of Medicine, Belgrade, Serbia., Yunis E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States., Brusic V; School of Computer Science, University of Nottingham Ningbo China, Ningbo, China., Shen Y; Department of Biomedical Informatics and Department of Systems Biology, Columbia University, New York, NY, United States., Keskin DB; Department of Translational Immuno-Genomics for Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, United States.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States., Najjar S; Department of Neurology, Lenox Hill Hospital, Northwell Health, New York, NY, United States., Stern JNH; Department of Neurology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Urology, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Molecular Medicine, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Department of Science Education, Donald and Barbra Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.; Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY, United States.
Publikováno v:
Frontiers in immunology [Front Immunol] 2022 Oct 04; Vol. 13, pp. 900605. Date of Electronic Publication: 2022 Oct 04 (Print Publication: 2022).