Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mandy L. Ford"'
Autor:
Jerome C. Anyalebechi, Yini Sun, Carolyn Davis, Maylene E. Wagener, Zhe Liang, Eileen M. Burd, Craig M. Coopersmith, Mandy L. Ford
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionA hallmark of T cell dysregulation during sepsis is the downregulation of costimulatory molecules. CD28 is one of T cell costimulatory molecules significantly altered on memory T cells during sepsis. We recently showed that treatment with
Externí odkaz:
https://doaj.org/article/429754ade8b144558594280f7c10d7ec
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionChronic alcohol use poses significant negative consequences to public health and, among its many biologic effects, is associated with significant T cell dysregulation within the adaptive immune system that has yet to be fully characterize
Externí odkaz:
https://doaj.org/article/373c77ea86584b28ad0dc557309905b3
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionCostimulation blockade targeting the CD28 pathway provides improved long-term renal allograft survival compared to calcineurin inhibitors but may be limited as CTLA-4-Ig (abatacept, belatacept) blocks both CD28 costimulation and CTLA-4 co
Externí odkaz:
https://doaj.org/article/6008c15a83eb49fe9b3460d521d029c6
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Sepsis is a major cause of morbidity and mortality worldwide despite numerous attempts to identify effective therapeutics. While some sepsis deaths are attributable to tissue damage caused by inflammation, most mortality is the result of prolonged im
Externí odkaz:
https://doaj.org/article/eacec016b2fb4b16906e15ed6bd170ad
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T cell co-signaling molecules play an important role in fine-tuning the strength of T cell activation during many types of immune responses, including infection, cancer, transplant rejection, and autoimmunity. Over the last few decades, intense resea
Externí odkaz:
https://doaj.org/article/7377052da5024e17889d676e744b61db
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology
Autor:
Mandy L. Ford, Scott M. Krummey
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Frontiers in Immunology
Frontiers in Immunology
Adaptive immunity in both mouse and man results in the generation of immunological memory. Memory T cells are both friend and foe to transplant recipients, as they are intimately involved and in many cases absolutely required for the maintenance of p
Autor:
Scott M. Krummey, Mandy L Ford
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Adaptive immunity in both mouse and man results in the generation of immunological memory. Memory T cells are both friend and foe to transplant recipients, as they are intimately involved and in many cases absolutely required for the maintenance of p
Externí odkaz:
https://doaj.org/article/ffe45c86773f477d81808f411422a98a