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pro vyhledávání: '"David A Hildeman"'
Autor:
Jana eRaynor, Allyson eSholl, David R. Plas, Philippe eBouillet, Claire A Chougnet, David A Hildeman
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
We and others have shown that regulatory T cells (Treg) accumulate dramatically with age in both humans and mice. Such Treg accrual contributes to age-related immunosenescence as they reduce the response to tumors and parasite infection. While we rep
Externí odkaz:
https://doaj.org/article/85157bf847c4483b8d20e0075840e5db
Autor:
Jana Raynor, Adora Lin, Sarah A. Hummel, Kristin Lampe, Michael Jordan, Kasper Hoebe, David A. Hildeman
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Increasing evidence points to a key role for NK cells in controlling adaptive immune responses. In studies examining the role of CD1d on CD4+ T cell responses, we found that a line of CD1d-deficient mice on the C57BL/6J background had a homozygous 12
Autor:
David A. Hildeman, David R. Plas, Allyson Sholl, Philippe Bouillet, Jana Raynor, Claire A. Chougnet
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology
Frontiers in Immunology
We and others have shown that regulatory T cells (Treg) accumulate dramatically with age in both humans and mice. Such Treg accrual contributes to age-related immunosenescence as they reduce the response to tumors and parasite infection. While we rep
Publikováno v:
Frontiers in Immunology, Vol 3 (2013)
Frontiers in Immunology
Frontiers in Immunology
Vaccines, arguably the single most important intervention in improving human health, have exploited the phenomenon of immunological memory. The elicitation of memory T cells is often an essential part of successful long-lived protective immunity. Our
Autor:
M. Eyad Khorki, Tiffany Shi, Eileen E. Cianciolo, Ashley R. Burg, P. Chukwunalu Chukwuma, Jennifer L. Picarsic, Mary K. Morrice, E. Steve Woodle, Jonathan S. Maltzman, Autumn Ferguson, Jonathan D. Katz, Brian M. Baker, David A. Hildeman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSignificant evidence suggests a connection between transplant rejection and the presence of high levels of pre-existing memory T cells. Viral infection can elicit viral-specific memory T cells that cross-react with allo-MHC capable of dri
Externí odkaz:
https://doaj.org/article/555d23a18c6843c39ebce9e0a10efea5