Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Abnormality"'
Autor:
Shiyu Sun, Yizhen Ji, Di Shao, Yasong Xu, Xiaomei Yang, Li Sun, Nan Li, Hui Huang, Qichang Wu
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
This study aimed to assess the efficiency of CNV-seq and WES in detecting genetic cause of congenital heart disease (CHDs) in prenatal diagnoses and to compare CNV detection rate between isolated and non-isolated CHD cases. We conducted a retrospecti
Externí odkaz:
https://doaj.org/article/c937794c9f7046c7815928c9322cdb89
Autor:
Yunsheng Ge, Jiayan Chen, Yanru Huang, Di Shao, Wenbo Wang, Meijiao Cai, Meihua Tan, Jian Zhang
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Fetal chromosomal abnormalities are the main cause of adverse pregnancy outcomes and are the focus of invasive prenatal diagnosis. Recent studies have demonstrated that various techniques have distinct advantages. Achieving high-resolution and effect
Externí odkaz:
https://doaj.org/article/81aee62e5a1c4754b05a2e0eb128a48f
Autor:
Na Liao, Zhu Zhang, Xijing Liu, Jiamin Wang, Rui Hu, Like Xiao, Yunyuan Yang, Yi Lai, Hongmei Zhu, Lingping Li, Shanling Liu, He Wang, Ting Hu
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Chromosomal abnormalities are a major cause of early pregnancy loss. However, models synthesizing existing genetic technologies to improve pregnancy outcomes are lacking. We aim to provide an integrated laboratory algorithm for the geneti
Externí odkaz:
https://doaj.org/article/c320e856584c4830a37c515de808b019
Autor:
Ying Chan, Yize Liu, Yamin Kong, Weiming Xu, Xiaohong Zeng, Haichun Li, Yan Guo, Xinhua Tang, Jinman Zhang, Baosheng Zhu
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: The genetic etiology of fetal chromosome abnormalities remains unknown, which brings about an enormous burden for patients, families, and society. The spindle assembly checkpoint (SAC) controls the normal procedure of chromosome disjuncti
Externí odkaz:
https://doaj.org/article/e2e63da7608444ba884310f4dc1de4ae
Autor:
Xin Li, Han Kang, Huifeng Yin, Tianjiao Liu, Qiannan Hou, Xiaolan Yu, Yuanlin Guo, Wei Shen, Huisheng Ge, Xiaoyan Zeng, Kangmu Lu, Ying Xiong
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Introduction: Though embryonic chromosome abnormalities have been reported to be the most common cause of missed abortions, previous studies have mainly focused on embryonic chromosome abnormalities of missed abortions, with very few studies reportin
Externí odkaz:
https://doaj.org/article/21165169dbbc4d46819d743fa308ac5b
Akademický článek
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Autor:
Lin Yang, Yan Xu, Jun Xia, Huijuan Yan, Chenhui Ding, Qianyu Shi, Yujing Wu, Ping Liu, Jiafu Pan, Yanhong Zeng, Yanyan Zhang, Fang Chen, Hui Jiang, Yanwen Xu, Wei Li, Canquan Zhou, Ya Gao
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Preimplantation genetic test for monogenic disorders (PGT-M) has been used to select genetic disease-free embryos for implantation during in vitro fertilization (IVF) treatment. However, embryos tested by PGT-M have risks of harboring chr
Externí odkaz:
https://doaj.org/article/e268629c06dc4d04ba5385c817b0f291
Autor:
Ting Hu, Jiamin Wang, Qian Zhu, Zhu Zhang, Rui Hu, Like Xiao, Yunyuan Yang, Na Liao, Sha Liu, He Wang, Xiaoyu Niu, Shanling Liu
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Objectives: The study aimed to investigate the clinical use of noninvasive prenatal testing (NIPT) for common fetal aneuploidies as a prenatal screening tool for the detection of rare chromosomal abnormalities (RCAs).Methods: Gravidas with positive N
Externí odkaz:
https://doaj.org/article/18b7c99ea00847c89f619cbfd3c1510a
Autor:
Sihan Liu, Yuanyuan Zeng, Chao Wang, Qian Zhang, Meilin Chen, Xiaolu Wang, Lanchen Wang, Yu Lu, Hui Guo, Fengxiao Bu
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
In clinical genetic testing, checking the concordance between self-reported gender and genotype-inferred gender from genomic data is a significant quality control measure because mismatched gender due to sex chromosomal abnormalities or misregistrati
Externí odkaz:
https://doaj.org/article/deecb6f2e7ff4cbb9c186379b580e3f4
Autor:
Yunyun Liu, Xiaosha Jing, Lingling Xing, Sha Liu, Jianlong Liu, Jing Cheng, Cechuan Deng, Ting Bai, Tianyu Xia, Xiang Wei, Yuan Luo, Quanfang Zhou, Qian Zhu, Hongqian Liu
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Background: We aimed to assess the clinical application of noninvasive prenatal screening (NIPS) based on second-trimester ultrasonographic soft markers (USMs) in low-risk pregnant women.Methods: Data of pregnant women between April 2015 and December
Externí odkaz:
https://doaj.org/article/e89df1af49764d90abd5af0919a49bad