Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Masafumi Ihara"'
Autor:
Akira Taniguchi, Akihiro Shindo, Ken-ichi Tabei, Osamu Onodera, Yukio Ando, Takao Urabe, Kazumi Kimura, Kazuo Kitagawa, Yoshihiro Miyamoto, Misa Takegami, Masafumi Ihara, Ikuko Mizuta, Toshiki Mizuno, Hidekazu Tomimoto
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
ObjectivesPatients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) show various clinical symptoms, including migraine, recurrent stroke, and cognitive impairment. We investigated the associati
Externí odkaz:
https://doaj.org/article/cd52335b25a34f74af81b82a76dc43d9
Autor:
Futoshi Eto, Takeshi Yoshimoto, Shuhei Okazaki, Kunihiro Nishimura, Shiori Ogura, Eriko Yamaguchi, Kazuki Fukuma, Satoshi Saito, Kazuo Washida, Masatoshi Koga, Kazunori Toyoda, Takaaki Morimoto, Hirofumi Maruyama, Akio Koizumi, Masafumi Ihara
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
IntroductionDysregulation of the RING finger protein 213 (RNF213) gene impairs vascular formation in experimental animal models. In addition, vascular abnormalities in the circle of Willis are associated with cerebrovascular disease. Here, we evaluat
Externí odkaz:
https://doaj.org/article/f60456a69efd4c98bad0322534d09e50
Autor:
Satoshi Saito, Yoshihiko Ikeda, Daisuke Ando, Roxana Octavia Carare, Hatsue Ishibashi-Ueda, Masafumi Ihara
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Cerebral amyloid angiopathy (CAA) is characterised by the progressive accumulation of β-amyloid (Aβ) in the walls of cerebral capillaries and arteries representing a major cause of haemorrhagic stroke including lobar intracerebral haemorrhage (ICH)
Externí odkaz:
https://doaj.org/article/64eb37147e604ccf8dadb1b47c72c229
Autor:
Akihiro Shindo, Ken-ichi Tabei, Akira Taniguchi, Hiroaki Nozaki, Osamu Onodera, Akihiko Ueda, Yukio Ando, Takao Urabe, Kazumi Kimura, Kazuo Kitagawa, Haruo Hanyu, Teruyuki Hirano, Hideaki Wakita, Hidenao Fukuyama, Tatsuo Kagimura, Yoshihiro Miyamoto, Misa Takegami, Satoshi Saito, Akiko Watanabe-Hosomi, Ikuko Mizuta, Masafumi Ihara, Toshiki Mizuno, Hidekazu Tomimoto
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
ObjectivesClinical characteristics of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) include migraine, recurrent stroke, white matter lesions, and vascular dementia. CADASIL is one of the most com
Externí odkaz:
https://doaj.org/article/a1f8c4a059694bcd83ac5ce930a8e510
Autor:
Takashi Okada, Kazuo Washida, Kenichi Irie, Satoshi Saito, Michio Noguchi, Tsutomu Tomita, Masatoshi Koga, Kazunori Toyoda, Shuhei Okazaki, Takashi Koizumi, Ikuko Mizuta, Toshiki Mizuno, Masafumi Ihara
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Objectives: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common hereditary small vessel disease, with reported frequencies of 2-5/100,000 individuals. Recently, it has been reported
Externí odkaz:
https://doaj.org/article/b048d0036cc44c1aad29dd14abfc0e82
Autor:
Masahiro Tsuji, Makiko Ohshima, Yumi Yamamoto, Satoshi Saito, Yorito Hattori, Emi Tanaka, Akihiko Taguchi, Masafumi Ihara, Yuko Ogawa
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
People with Down syndrome, which is a trisomy of chromosome 21, exhibit intellectual disability from infancy and neuropathology similar to Alzheimer’s disease, such as amyloid plaques, from an early age. Recently, we showed that cilostazol, a selec
Externí odkaz:
https://doaj.org/article/05ac80529cf448cb93db6cef1c42fa94
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Pericytes are unique, multi-functional mural cells localized at the abluminal side of the perivascular space in microvessels. Originally discovered in 19th century, pericytes had drawn less attention until decades ago mainly due to lack of specific m
Externí odkaz:
https://doaj.org/article/802476aa3787484a9a99a08507a1ffeb
Autor:
Satoshi Saito, Masafumi Ihara
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 6 (2014)
Frontiers in Aging Neuroscience, Vol 6 (2014)
Accumulating evidence has shown a strong relationship between Alzheimer’s disease (AD), cerebral amyloid angiopathy (CAA), and cerebrovascular disease. Cognitive impairment in AD patients can result from cortical microinfarcts associated with CAA,