Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lester Packer"'
Autor:
Yuko Terasawa, Jacob Raber, Maret G. Traber, Robert V. Farese, Carroll E. Cross, Abhishek A Chakraborty, Lester Packer, Kishorchandra Gohil, Bettina C. Schock
Publikováno v:
Free radical biologymedicine. 35(11)
Alpha-tocopherol transfer protein (TTP) regulates the retention and secretion of alpha-tocopherol (alpha-T) by the liver. Deletion of the TTP gene (Ttpa) in mice results in systemic deficiency of alpha-T and neurological dysfunctions described in pat
Autor:
Ana M. Corbacho, Elisa Pagnin, Lester Packer, Giuseppe Valacchi, Estibaliz Olano, Carroll E. Cross, Paul A. Davis
Publikováno v:
Free radical biologymedicine. 36(5)
Lung and skin are the organs directly exposed to environmental pollution. Ozone (O(3)) is a toxic, oxidant air pollutant, and exposure has been shown to induce antioxidant depletion as well as oxidation of lipids and proteins within the outermost ski
Autor:
Maurizio Podda, T Herrling, N. Groth, Jürgen Fuchs, Lester Packer, Roland Kaufmann, Stefan U. Weber
Publikováno v:
Free radical biologymedicine. 34(3)
The content and composition of different vitamin E isoforms was analyzed in normal human skin. Interestingly the epidermis contained 1% alpha-tocotrienol, 3% gamma-tocotrienol, 87% alpha-tocopherol, and 9% gamma-tocopherol. Although the levels of toc
Autor:
Chate Luu, Jens J. Thiele, Nancy Han, Lester Packer, Stefan Weber, Stefanie Weber, Giuseppe Valacchi
Publikováno v:
Free radical biologymedicine. 34(2)
Benzoyl peroxide (BPO) is a commonly used drug in the treatment of acne vulgaris, but it induces unwanted side effects related to stratum corneum (SC) function. Since it has been recently shown to oxidize SC antioxidants, it was hypothesized that ant
Publikováno v:
Free radical biologymedicine. 30(9)
In the present study, the effects of 4-hydroxy-2-nonenal (HNE) on highly purified pyruvate dehydrogenase complex (PDC) and its catalytic components in vitro and on PDC, alpha-ketoglutarate dehydrogenase complex (KGDC), and the branched-chain alpha-ke
Publikováno v:
Free radical biologymedicine. 28(2)
Expression of intercellular adhesion molecule-1 (ICAM-1) is necessary for leukocyte/keratinocyte interactions. Upregulation of ICAM-1 expression in keratinocytes has been observed in several inflammatory dermatoses, such as psoriasis, atopic dermatit
Autor:
Fabio Virgili, Catherine Rice-Evans, George Pagana, Lester Packer, Fausta Natella, Louise Bourne, Gerald Rimbach
Publikováno v:
Free radical biologymedicine. 28(8)
French maritime pine (Pinus maritima) bark extract (PBE) is a polyphenol-rich food supplement patented under the name of Pycnogenol and known to have strong antioxidant activity and different beneficial effects on human health. Although its biologica
Publikováno v:
Free radical biologymedicine. 27(11-12)
The free radical generated from the oxidation of a French maritima pine bark extract Pycnogenol (PYC), by the horseradish peroxidase (HRP)-hydrogen peroxide (H2O2) system at pH 7.4-10.0 was studied using electron spin resonance (ESR) spectrometer. Th
Publikováno v:
Free radical biologymedicine. 27(5-6)
There is growing interest in the biologic activities of plant extracts such as that obtained from the bark of the French maritime pine Pinus maritima, Pycnogenol. Pycnogenol (PYC) is a standardized extract composed of a mixture of flavonoids, mainly
Autor:
Lester Packer, Jürgen Fuchs
Publikováno v:
Free radical biologymedicine. 27(3-4)
Solar radiation induces suppression of the local effector mechanisms involved in immune responses to recall antigens. By using a low-dose solar-simulated radiation protocol, we investigated whether oral supplementation of the antioxidants RRR-α-toco