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of 5
pro vyhledávání: '"John S"'
Publikováno v:
FEBS Letters. 444:155-159
Salmon insulin-like growth factor-I (sIGF-I) expression is, as in mammals, induced by growth hormone (GH). To elucidate the mechanism by which GH stimulates the transcription of the IGF-I gene, we transiently transfected Hep3B cells expressing the ra
Autor:
John S. Sussenbach, Werner E.G. Müller, Alexey Y. Palamarchuk, Vadim M. Kavsan, P. Elly Holthuizen
Publikováno v:
FEBS Letters. 416:344-348
IGF-II plays an important role in growth and development of vertebrates. In the present study, the characterization of the first fish IGF-II gene, chum salmon IGF-II, is described. The sIGF-II gene consists of four exons, spanning a region of 9 kbp,
Publikováno v:
FEBS Letters. 394:25-30
The adult liver-specific IGF-II promoter P1 is activated by CCAAT/Enhancer Binding Proteins α and β. Here we present evidence that promoter P1, in addition to positively regulating elements, contains two elements of 67 nucleotides that form an inve
Publikováno v:
FEBS Letters. (2-3):251-255
IGF-II plays an important role in growth and development of vertebrates and is highly expressed in adult salmon liver. In the present study, we demonstrate that a liver-enriched transcription factor, hepatocyte nuclear factor 3beta (HNF-3beta), is an
Autor:
R.A. van der Kammen, F.M.A. van Schaik, C. Oosterwijk, P. de Pagter-Holthuizen, J.L. Van den Brande, Marnix Jansen, John S. Sussenbach
Publikováno v:
FEBS Letters, 214(2), 259. Elsevier
The insulin-like growth factors (IGF) play an important role in fetal and postnatal development. Recently, the nucleotide sequences of the cDNAs encoding IGF-I and IGF-II and part of the human IGF genes were reported. In this communication we describ