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Publikováno v:
FEBS letters. 591(1)
Rat perivascular adipose tissue (PVAT) stores, takes up, and releases norepinephrine (NE; Ayala-Lopez et al. (2014) Pharmacol Res Perspect 2, e00041). We hypothesized that 3T3-L1 adipocytes would exhibit similar behaviors and, thus, could serve as a
Autor:
Yasuhiro Umemura, Wataru Nakamura, Nobuya Koike, Yutaka Inada, Kazuhiro Yagita, Takayoshi Sakai, Hitoshi Uchida
Publikováno v:
FEBS Letters. 588:459-465
The emergence of the circadian rhythm is a dramatic and physiologically essential event for mammals to adapt to daily environmental cycles. It has been demonstrated that circadian rhythms develop during the embryonic stage even when the maternal cent
Autor:
Nikolaos N. Louros, Vassiliki A. Iconomidou, Stavros J. Hamodrakas, Paraskevi L. Tsiolaki, Efstratios Patsouris, Georgios Baltatzis, Evangelia D. Chrysina
Publikováno v:
FEBS Letters. 588:52-57
Isolated atrial amyloidosis (IAA) is a common localized form of amyloid deposition within the atria of the aging heart. The main constituents of amyloid fibrils are atrial natriuretic peptide (ANP) and the N-terminal part of its precursor form (NT-pr
Publikováno v:
FEBS Letters. 587:3853-3858
Adipocytes are continuously stimulated by proinflammatory cytokines such as TNFα, which cause adipocyte dysfunction by facilitating the inflammatory response. Although miR-130 was reported to be an important regulator of adipogenesis by targeting PP
Autor:
Alejandra Gorostizaga, Mercedes Mori Sequeiros García, Carlos F. Mendez, Cristina Paz, Andrea Acquier
Publikováno v:
FEBS Letters. 587:3254-3260
Intrarenally-produced dopamine (DA) induces a large increase in urinary sodium excretion mainly due to the inhibition of tubular sodium reabsorption. We aimed to study the participation of reactive oxygen species (ROS) in DA signaling pathway in prox
Autor:
Maria João Saraiva, Marta Vieira
Publikováno v:
FEBS Letters. 587:1482-1488
Transthyretin is the carrier protein of thyroxine and retinol in plasma and cerebrospinal fluid and has been described also as a neuroprotective molecule. 14-3-3 Proteins are very important in many cellular processes, being their absence related with
Publikováno v:
FEBS Letters. 587:1392-1398
The 24-h rhythmic production of melatonin by the pineal gland is essential for coordinating circadian physiology. Melatonin production increases at night in response to the release of norepinephrine from sympathetic nerve processes which innervate th
Autor:
Tasuku Kanai, Toshihiko Yanagita, Shinya Satoh, Manabu Murakami, Chihiro Sugita, Takayuki Nemoto, Akihiko Wada, Toyoaki Maruta
Publikováno v:
FEBS Letters. 587:898-905
Endothelin-1 and voltage-dependent sodium channels are involved in control and suppression of neuropathological factors, which contribute to sculpting the neuronal network. We previously demonstrated that veratridine-induced NaV1.7 sodium channel act
Autor:
Arup K. Indra, Stephen Hyter
Publikováno v:
FEBS Letters. 587:529-541
Skin homeostasis is maintained, in part, through regulation of gene expression orchestrated by type II nuclear hormone receptors in a cell and context specific manner. This group of transcriptional regulators is implicated in various cellular process
Publikováno v:
FEBS letters
FEBS LETTERS
FEBS LETTERS
In this review, we discuss genetic evidence supporting Guyton’s hypothesis stating that blood pressure control is critically depending on fluid handling by the kidney. The review is focused on the genetic dissection of sodium and potassium transpor