Zobrazeno 1 - 10
of 310
pro vyhledávání: ''
Autor:
Takanobu Taniguchi, Susanne M. Krug, Michael Fromm, Rafiqul Islam Khan, Yuichi Suzuki, Hatsumi Yoshiki, Tariqul Islam, Ikunobu Muramatsu, Shin-ichiro Karaki, Abu Syed Md Anisuzzaman, Atsukazu Kuwahara, Takashi Yazawa, Junsuke Uwada, Kiyonao Sada
Publikováno v:
FEBS Letters. 589:3640-3647
Impaired intestinal barrier function is one of the critical issues in inflammatory bowel diseases. The aim of this study is to investigate muscarinic cholinoceptor (mAChR)-mediated signaling for the amelioration of cytokine-induced barrier dysfunctio
Publikováno v:
FEBS letters. 591(1)
Rat perivascular adipose tissue (PVAT) stores, takes up, and releases norepinephrine (NE; Ayala-Lopez et al. (2014) Pharmacol Res Perspect 2, e00041). We hypothesized that 3T3-L1 adipocytes would exhibit similar behaviors and, thus, could serve as a
Publikováno v:
FEBS Letters. 587:3853-3858
Adipocytes are continuously stimulated by proinflammatory cytokines such as TNFα, which cause adipocyte dysfunction by facilitating the inflammatory response. Although miR-130 was reported to be an important regulator of adipogenesis by targeting PP
Autor:
Yoko Okafuji, Kazuo Inoue, Satoshi Tsuzuki, Takafumi Mizushige, Shigenobu Matsumura, Ai Eguchi, Sotaro Tatsu, Tohru Fushiki
Publikováno v:
FEBS Letters. 586:1231-1235
The opioid system regulates food choice, consumption, and reinforcement processes, especially for palatable meals such as fatty food. β-Endorphin is known as an endogenous opioid peptide produced in neurons of the hypothalamus. In this study, we fou
Autor:
Axel Ullrich, Indranil Bhattacharya
Publikováno v:
FEBS Letters. 580:5765-5771
In adipogenesis, growth factors play a crucial role. Using serum depleted condition, we studied the causal role of endothelin-1 (ET-1) and epidermal growth factor (EGF), separately or together, in adipocyte differentiation of 3T3-L1 cells. ET-1 stimu
Publikováno v:
FEBS Letters. 580:1509-1514
Different C-terminal fragments of parathyroid hormone (PTH)-(1–84) in blood participate in the regulation of calcium homeostasis by PTH-(1–84), and an antagonizing effect for the large carboxyl-terminal parathyroid hormone (C-PTH)-fragment (7–8
Publikováno v:
FEBS Letters. 576:156-160
We previously demonstrated that chronic stimulation of the beta2-adrenergic receptor (beta2-AR) increases proliferation of cultured human cardiac fibroblasts (CF) via an autocrine mechanism. Here, we investigated the role of endothelin-1 (ET-1) in th
Myometrial maxi-K channel β1 subunit modulation during pregnancy and after 17β-estradiol stimulation
Publikováno v:
FEBS Letters. 524:97-102
Myometrial maxi-K channels are modulated by beta subunits. We aimed to determine whether beta subunits are modulated to affect uterine excitability during gestation. RNase protection analyses revealed that mouse beta1 subunit transcripts are regulate
Publikováno v:
FEBS Letters. 508:57-60
Urotensin II (UII), a cyclic neuropeptide, functions not only in the central nervous system but also in non-neural systems including cardiovascular systems. In the present study we examined whether UII regulates hypertrophy in cardiomyocytes. The exp
Autor:
Jesús García, Vincenzo Sorrentino, Xinsheng Zhu, Daniela Rossi, Héctor H. Valdivia, Ilenia Simeoni
Publikováno v:
FEBS Letters. 508:5-10
The effect of imperatoxin A (IpTx(a)) on the ryanodine receptor type 3 (RyR3) was studied. IpTx(a) stimulates [(3)H]ryanodine binding to RyR3-containing microsomes, but this effect requires toxin concentrations higher than those required to stimulate