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Autor:
Chen-Yu Zhang, Chang Liu, Chunni Zhang, Pingping Shen, Peixiang Zhang, Junfeng Zhang, Yan Zhang
Publikováno v:
FEBS Letters. 579:1446-1452
PGC-1alpha mRNA and protein are elevated in islets from multiple animal models of diabetes. Overexpression of PGC-1alpha impairs glucose-stimulated insulin secretion (GSIS). However, it is not well known which metabolic events lead to upregulation of
Publikováno v:
FEBS Letters. 519:227-230
The mechanism underlying lipopolysaccharide (LPS)-induced depression of phosphoinositide (PI) hydrolysis was investigated using rat aortas. In LPS-pretreated aortas, the 5-hydroxytryptamine-stimulated accumulation of inositol monophosphate and incorp
Autor:
Yumiko Urakami, Yukiya Hashimoto, Ken-ichi Inui, Nobuhiko Nakamura, Masahiro Okuda, Kazushige Takahashi, Hideyuki Saito
Publikováno v:
FEBS Letters. 461:339-342
The organic cation transporter (OCT) mediates translocation of various cationic molecules including drugs, toxins and endogenous substances. We examined gender differences in the expression of rat (r) OCT2 in the kidney. Slices and basolateral membra
Publikováno v:
FEBS Letters. 449:273-276
The expression of the cellular protooncogene c-ski was examined in the rat uterus. In situ hybridization revealed that c-ski mRNA was expressed in the uterus of the adult rat on the day of estrous and localized mainly in the luminal and glandular epi
Publikováno v:
FEBS Letters. 439:163-167
Transcription levels of the non-specific δ-aminolevulinate synthase (ALAS-N) and heme oxygenase-1 (HO-1) in the placenta at the terminal stage of pregnancy were comparable to those in the female adult liver and in the spleen, respectively. Immunohis
Autor:
Michael Horster, Gerald S. Braun, Anke Burger-Kentischer, Stephan Huber, Brigitte Reinhart, Bruno Luckow
Publikováno v:
FEBS Letters. 423:362-366
The collecting duct epithelium originates from the embryonic ureter by branching morphogenesis. Ontogeny-dependent changes of CFTR mRNA expression were assessed by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) in primary monol
Autor:
Roser Iglesias, Angels Grado, Teresa Mampel, Carles Manchado, Marta Giralt, Francesc Villarroya, Octavi Viñas
Publikováno v:
FEBS Letters. 421:213-216
A postnatal increase in the content of mitochondrial ANT in rat liver which is related to the maturation of mitochondrial function has previously been reported [Schönfeld et al., Biochim. Biophys Acta 1144 (1993) 353–358]. In order to define the c
Publikováno v:
FEBS Letters. 418:265-268
In rat liver, a single serine:pyruvate/alanine:glyoxylate aminotransferase (SPT or SPT/AGT) gene is transcribed from two transcription initiation sites. Transcription from the upstream site generates the mRNA encoding the precursor for mitochondrial
Autor:
H. Rothe, Victoria Kolb-Bachofen, Hubert Kolb, Qiao-wen Xie, Robert Kleemann, Carl Nathan, Stephan Martin
Publikováno v:
FEBS Letters. 328:9-12
The inducible NO synthase (iNOS) was found to be expressed in pancreatic lesions of adult diabetes-prone BB rats. Pancreatic iNOS mRNA was detected by reverse transcriptase PCR in pancreatic RNA of adult diabetes-prone BB rats but not in normal Wista
Autor:
José M. Cuezva, José M. Izquierdo
Publikováno v:
FEBS Letters. 323:109-112
Thyroid hormones acutely regulate gene expression of the beta-catalytic subunit of the mitochondrial F1-ATPase complex in the liver of hypothyroid rat neonates at either a transcriptional and/or post-transcriptional level [(1990) J. Biol. Chem. 265,