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Autor:
Shoaib Chowdhury, Masaki Takiguchi, Katsuro Iwase, Seiichi Oyadomari, Motoaki Shichiri, Masataka Mori, Fumihiko Matsuno, Tatsuya Kimura, Eiichi Araki
Publikováno v:
FEBS Letters. 478:141-146
The gene for a transcription factor hepatocyte nuclear factor-4alpha (HNF-4alpha) is responsible for maturity-onset diabetes of the young, type 1. We examined hormonal regulation of the HNF-4alpha gene in the liver. Stimulation of primary-cultured ra
Publikováno v:
FEBS Letters. 371:324-328
ob gene regulation is as yet unknown. We first examined whether the ob gene is under physiological control by the nutritional state. Fasting produced a sharp (95%) decrease of ob mRNA in epididymal and inguinal fat pads from 24 h onward. Refeeding ra